Baer(Richard),Ludwig(Thomas) Curr Opin Genet Dev 2002-04-11

...BARD1 as enzymatic mediators of protein ubiquitination. The potent ubiquitin E3 ligase activity of the BRCA1/BARD1 heter...

Chiba(Natsuko),Parvin(Jeffrey D) Cancer Res 2002-09-11

...BARD1) is a component of the holo-pol complex. Deletion of the BRCA1 NH(2) terminus, which is bound by BARD1 as well as ...

Oyake(Daisuke),Nishikawa(Hiroyuki),Koizuka... Biochem Biophys Res Commun 2002-08-29

...BARD1 linked to a substrate recognition site PCNA, which is known to interact with cyclin-dependent kinase inhibitor p57...

Liu(Yilun),West(Stephen C) Breast Cancer Res 2002-12-27

...BARD1 proteins, and suggest that the pleiotropic nature of mutations in BRCA1 may be associated with defects in protein-...

Irminger-Finger(Irmgard),Leung(Wai Choi) Int J Biochem Cell Biol 2002-09-05

...BARD1 is strongly expressed in spleen and testis, correlated with the expression of BRCA1. Co-localization of BARD1 with...

Chen(Angus),Kleiman(Frida E),Manley(James ... J Biol Chem 2002-07-25

...BARD1 in bacteria can assemble a potent ubiquitin ligase activity. Purified BRCA1-(1-639)*BARD1 stimulated the Ubc5c-med...

Fabbro(Megan),Rodriguez(Jose A),Baer(Richa... J Biol Chem 2002-07-25

...BARD1, and this is not affected by cancer-associated RING mutations. Moreover, BARD1 directly masks the BRCA1 nuclear ex...

Morris(Joanna R),Keep(Nicholas H),Solomon(... J Biol Chem 2002-04-05

...BARD1 at its N terminus. In cells BRCA1 is found as a heterodimer with BARD1 and may represent the functionally active f...

Irminger-Finger(I),Leung(W C),Li(J),Dubois... Mol Cell 2002-01-16

...BARD1 protein and mRNA; (2) overexpression of BARD1 induces cell death with all features of apoptosis; and (3) BARD1-rep...

Gautier(F),Irminger-Finger(I),Grégoire(M),... Cancer Res 2001-02-22

...BARD1 is located NH2 terminally but downstream of the RING domain essential for BARD1 and BRCA1 protein interaction. In ...