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MSH3-deficiency initiates EMAST without oncogenic transformation of human colon…

Campregher(Christoph),Schmid(Gerald),Ferk(Fr… PLoS One 2013-05-22

...RAD50), apoptosis, L1 recycling, and repression of proteins involved in metabolism, tRNA aminoacylation, and gene expres...

Femtomolar Zn(II) affinity of minimal zinc hook peptides--a promising small tag…

Kochańczyk(Tomasz),Jakimowicz(Piotr),Krężel(… Chem Commun (Camb) 2013-08-14

...Rad50 and its alanine mutants form highly stable Zn(II) complexes. These peptides were successfully used as a small, eff...

Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is req…

Leung(Justin Wai-Chung),Ghosal(Gargi),Wang(W… J Biol Chem 2013-05-09

...RAD50-NBS1 (MRN) complex. Together, these results suggest a non-canonical function of ATRX in guarding genomic stability...

The type of mutations induced by carbon-ion-beam irradiation of the filamentous…

Ma(Liqiu),Kazama(Yusuke),Inoue(Hirokazu),Abe… Fungal Biol 2013-11-12

...Rad50-Xrs2 (MRX) complex, were irradiated with a carbon-ion beam and killing effect, mutation frequencies, and the type ...

NBS1 rs1805794G>C polymorphism is associated with decreased risk of acute myelo…

Li(Na),Xu(Yanzhe),Zheng(Jian),Jiang(Lan),You… Mol Biol Rep 2013-09-13

...RAD50-NBS1) complex, NBS1 plays a crucial role in maintaining genomic stability and preventing cell apoptosis, inflammat...

MRX protects fork integrity at protein-DNA barriers, and its absence causes che…

Bentsen(Iben B),Nielsen(Ida),Lisby(Michael),… Nucleic Acids Res 2013-05-02

...Rad50, Xrs2) complex for fork integrity at RFBs, which differs from its acknowledged function in double-strand break pro...

Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cyto…

Williams(Adam),Lee(Gap Ryol),Spilianakis(Cha… Proc Natl Acad Sci U S A 2013-06-27

...Rad50 hypersensitive site 6 was the singularly most important HS for Th2 cytokine expression, displaying consistent redu...

Tel1 and Rad51 are involved in the maintenance of telomeres with capping defici…

Di Domenico(Enea Gino),Mattarocci(Stefano),C… Nucleic Acids Res 2013-09-20

...Rad50. Generation of telomeric G-tail, which is cell cycle regulated, depends on the MRX (Mre11-Rad50-Xrs2) complex in t...

Coincident resection at both ends of random, γ-induced double-strand breaks req…

Westmoreland(James W),Resnick(Michael A) PLoS Genet 2013-06-25

...Rad50/Xrs2 complex (MRX) at random DSBs in circular chromosomes within budding yeast based on reduced pulsed-field gel e...

Multiple genetic pathways regulate replicative senescence in telomerase-deficie…

Ballew(Bari J),Lundblad(Victoria) Aging Cell 2013-12-16

...Rad50-Xrs2) complex, as well as negative (Rif2) and positive (Tel1) regulators of this complex, comprise a single pathwa...

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