...BRCA1; however, expression of ERCC1 was significantly associated with that of BRCA1 in this set of Chinese patients with...
...BRCA1, BRCA2, FANC-C, FANC-F, FANC-L, ATM, MGMT, hMLH1 and H2AX except for two cases of minor BRCA1 hypermethylation. CL...
...BRCA1 expression and age (χ(2) = 4.14, P = 0.04) and stage (χ(2) = 5.26, P = 0.02). Our results suggest that ERCC1 and B...
The inactivation of BRCA1 by epigenetic alterations is a critical event in breast tumorigenesis, which may potentially b...
...BRCA1 deficiency in this cohort. Using signatures derived from the meta-analysis of TNBC gene expression carried out by ...
...BRCA1, ATM and TP53 have been associated with metastasis by a number of in vitro biochemical and cellular assays, by exa...
...BRCA1/2) through an approach termed "synthetic lethality." In the midst of the tremendous efforts that have brought PARP...
...BRCA1/2 status and observed a statistically significant reduced risk in the non-carriers only.,We observed a decreased r...
...BRCA1 and BRCA2). Not only do mutations in BRCA genes increase the risk of PCa, but they have also been related to adver...
The Breast Cancer Susceptibility Genes, BRCA1 and BRCA2, are the dynamic regulators of genomic integrity. Inherited muta...
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