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Association between epidermal growth factor receptor gene copy number and ERCC1…

Zhang(Yalei),Yang(Haihong),Qiu(Yuan),Deng(Qi… Med Oncol 2014-09-30

...BRCA1; however, expression of ERCC1 was significantly associated with that of BRCA1 in this set of Chinese patients with...

Poly(ADP-ribose) polymerase inhibitor CEP-8983 synergizes with bendamustine in …

Dilley(Robert L),Poh(Weijie),Gladstone(Dougl… Leuk Res 2014-04-21

...BRCA1, BRCA2, FANC-C, FANC-F, FANC-L, ATM, MGMT, hMLH1 and H2AX except for two cases of minor BRCA1 hypermethylation. CL...

ERCC1 and BRCA1 mRNA expressions are associated with clinical outcome of non-sm…

Qin(Xiuguang),Yao(Wenjian),Li(Weiwei),Feng(X… Tumour Biol 2014-06-24

...BRCA1 expression and age (χ(2) = 4.14, P = 0.04) and stage (χ(2) = 5.26, P = 0.02). Our results suggest that ERCC1 and B...

Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysi…

Wu(Liang),Wang(Fengliang),Xu(Ruobing),Zhang(… Breast Cancer Res Treat 2014-07-18

The inactivation of BRCA1 by epigenetic alterations is a critical event in breast tumorigenesis, which may potentially b...

Molecular phenotypes in triple negative breast cancer from African American pat…

Lindner(Robert),Sullivan(Catherine),Offor(On… PLoS One 2014-07-07

...BRCA1 deficiency in this cohort. Using signatures derived from the meta-analysis of TNBC gene expression carried out by ...

DNA damage response genes and the development of cancer metastasis.

Broustas(Constantinos G),Lieberman(Howard B) Radiat Res 2014-05-02

...BRCA1, ATM and TP53 have been associated with metastasis by a number of in vitro biochemical and cellular assays, by exa...

Structural Implications for Selective Targeting of PARPs.

Steffen(Jamin D),Brody(Jonathan R),Armen(Rog… Front Oncol 2014-06-24

...BRCA1/2) through an approach termed "synthetic lethality." In the midst of the tremendous efforts that have brought PARP...

Oral contraceptive and reproductive risk factors for ovarian cancer within sist…

Ferris(J S),Daly(M B),Buys(S S),Genkinger(J … Br J Cancer 2014-04-15

...BRCA1/2 status and observed a statistically significant reduced risk in the non-carriers only.,We observed a decreased r...

Clinical features and management of BRCA1 and BRCA2-associated prostate cancer.

Alanee(Shaheen R),Glogowski(Emily A),Schrade… Front Biosci (Elite Ed) 2014-08-25

...BRCA1 and BRCA2). Not only do mutations in BRCA genes increase the risk of PCa, but they have also been related to adver...

The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.

Paul(Arindam),Paul(Soumen) Front Biosci (Landmark Ed) 2014-09-15

The Breast Cancer Susceptibility Genes, BRCA1 and BRCA2, are the dynamic regulators of genomic integrity. Inherited muta...

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