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Enhanced levels of double-strand DNA break repair proteins protect ovarian canc…

Kalra(Rajkumar Singh),Bapat(Sharmila A) J Ovarian Res 2013-11-15

...RAD50, NPM1, and XRCC5 in transformed cells over pre-transformed, non-tumorigenic cells. Analysis of the functional rele...

Analysis of the effect of radiation repair mutations on the DEL1 mutator region…

Downs(K M),Szwast(A E),Liebman(S W) Curr Genet 2013-11-01

...rad50-1, and rad51-1, toDEL1 and asked whether DEL1 was still functional. We found that none of these rad mutations sign...

Isolation and characterization of yeast DNA repair genes : II. Isolation of pla…

Calderon(I L),Contopoulou(C R),Mortimer(R K) Curr Genet 2013-11-01

...rad50-1 complementing plasmid failed to integrate at the RAD50 locus, indicating that no homology exists between this fr...

ATP and AMP mutually influence their interaction with the ATP-binding cassette …

Randak(Christoph O),Dong(Qian),Ver Heul(Aman… J Biol Chem 2013-11-26

...Rad50 and a structural maintenance of chromosome protein, also have adenylate kinase activity. All three ABC adenylate k...

Femtomolar Zn(II) affinity of minimal zinc hook peptides--a promising small tag…

Kochańczyk(Tomasz),Jakimowicz(Piotr),Krężel(… Chem Commun (Camb) 2013-08-14

...Rad50 and its alanine mutants form highly stable Zn(II) complexes. These peptides were successfully used as a small, eff...

Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is req…

Leung(Justin Wai-Chung),Ghosal(Gargi),Wang(W… J Biol Chem 2013-05-09

...RAD50-NBS1 (MRN) complex. Together, these results suggest a non-canonical function of ATRX in guarding genomic stability...

Haplotype analysis of eight genes of the monoubiquitinated FANCD2-DNA damage-re…

Tang(Li-Li),Chen(Fei-Yu),Wang(Hao),Hu(Xue-Li… Cancer Epidemiol 2013-11-06

...RAD50, BRIP1, and PALB2. Genotyping was performed by SNPscan on 734 female patients and 672 female age-matched controls....

Genetic manipulation in Sulfolobus islandicus and functional analysis of DNA re…

Zhang(Changyi),Tian(Bin),Li(Suming),Ao(Xiang… Biochem Soc Trans 2013-08-02

...Rad50, Mre11, HerA, NurA and Hjc, only the Hjc nuclease is dispensable for cell viability. Sulfolobus encodes redundant ...

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces ty…

Kondo(Takeshi),Kobayashi(Junya),Saitoh(Tatsu… Proc Natl Acad Sci U S A 2013-04-26

...RAD50, a binding protein to MRE11, was also required for dsDNA responses, whereas NBS1, another binding protein to MRE11...

Processing of DNA double-stranded breaks and intermediates of recombination and…

Ghodke(Indrajeet),Muniyappa(K) J Biol Chem 2013-06-13

Saccharomyces cerevisiae RAD50, MRE11, and XRS2 genes are essential for telomere length maintenance, cell cycle checkpoi...

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