...BRCA1 or BRCA2 mutations. The nine exons of the RAD51C gene containing protein coding sequence were screened for mutatio...
...BRCA1 mutations. Knockdown of BRCA1 in MCF7 cells increases the amount of phospho-AKT and sensitizes cells to small mole...
...BRCA1-mediated epigenetic repression at the promoter region of miRNA-155 was identified as a novel mechanism by which BR...
...BRCA1 and BRCA2 genes have significantly increased lifetime risks of breast and ovarian cancer. To manage both the ovari...
Polymorphic BRCA1 is a vital tumor suppressor gene within the DNA double-strand break repair pathways, but its associati...
...BRCA1, and Ku80), concomitantly with the occurrence of microsatellite instability while maintaining telomere length. We ...
...BRCA1 and p53 statuses. BRCA1-competent breast cancer cell lines exhibited different responses to topoisomerase II inhib...
...BRCA1/2 testing. We also explored what type of resources participants would have valued to help in supporting family com...
...BRCA1 in all three genetic groups. In primary cultures of FTE from women with BRCA1 mutation or wildtype for BRCA1 and B...
...BRCA1/BRCA2-negative familial breast cancer cases. We identified a single splice site mutation (c.2013+2T>A), which caus...
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