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RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2…

Lok(B H),Carley(A C),Tchang(B),Powell(S N) Oncogene 2013-10-01

...BRCA1 or PALB2, which implicates BRCA1, PALB2 and BRCA2 in an epistatic relationship with one another. When RAD52 was de...

The single nucleotide polymorphisms in BRAP decrease the risk of metabolic synd…

Wu(Lijun),Xi(Bo),Hou(Dongqing),Zhao(Xiaoyuan… Diab Vasc Dis Res 2013-10-21

...BRCA1)-associated protein (BRAP) are significantly associated with coronary artery disease, but the molecular mechanisms...

BRCA1/2 mutations appear embryo-lethal unless rescued by low (CGG n<26) FMR1 su…

Weghofer(Andrea),Tea(Muy-Kheng),Barad(David … PLoS One 2013-03-12

BRCA1/2 mutations and recently described constitutional FMR1 genotypes have, independently, been associated with prematu...

Evaluation of candidate biomarkers to predict cancer cell sensitivity or resist…

Oplustilova(Lenka),Wolanin(Kamila),Mistrik(M… Cell Cycle 2013-03-01

...BRCA1- or BRCA2-defective tumors (hence defective in DNA repair by homologous recombination, HR) to inhibitors of the po...

Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein a…

Neumeister(Veronique M),Sullivan(Catherine A… Breast Cancer Res Treat 2013-05-23

...BRCA1 function in triple negative breast cancer (TNBC). Protein expression of CA IX and BRCA1 was evaluated by AQUA™ tec...

Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.

Aynaud(Marie-Ming),Suspène(Rodolphe),Vidalai… J Biol Chem 2013-01-31

...BRCA1-ATM network. TRIB3 emerges as an important guardian of genome integrity.

Prostate cancer: germline prediction for a commonly variable malignancy.

Bambury(Richard M),Gallagher(David J) BJU Int 2013-02-05

...BRCA1, BRCA2 and HOXB13 can affect prostate cancer incidence and/or clinical behaviour. Genome wide association studies ...

High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in i…

Madjd(Zahra),Ramezani(Babak),Molanae(Saadat)… Asian Pac J Cancer Prev 2013-02-27

...BRCA1 expression showed a significant inverse association between the two, indicating that reduced BRCA1 was more often ...

Support of the 'fallopian tube hypothesis' in a prospective series of risk-redu…

Reitsma(Welmoed),de Bock(Geertruida H),Ooste… Eur J Cancer 2013-02-27

...BRCA1-carriers, 115 BRCA2-carriers and 57 BRCA-negative women at a median age of 44.0 years. Four occult invasive cancer...

Development of a next-generation sequencing method for BRCA mutation screening:…

Chan(Maurice),Ji(Shen Mo),Yeo(Zhen Xuan),Gan… J Mol Diagn 2013-02-28

...BRCA1 and BRCA2 genes, generated using a PCR-based, multiplexed NGS approach using the SOLiD 4 (n = 24) and Ion Torrent ...

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