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BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degra…

Shabbeer(S),Omer(D),Berneman(D),Weitzman(O),… Oncogene 2013-12-23

...BRCA1 E3 ligase in these cellular functions is poorly understood. We present data showing that BRCA1 ubiquitinates G2/M ...

53BP1 regulates DSB repair using Rif1 to control 5' end resection.

Zimmermann(Michal),Lottersberger(Francisca),… Science 2013-02-20

...BRCA1/BARD1 complexes at sites of DNA damage; and defines one of the mechanisms by which 53BP1 causes chromosomal abnorm...

Early onset breast cancer in a registry-based sample of African-american women:…

Pal(Tuya),Bonner(Devon),Kim(Jongphil),Montei… Breast J 2013-09-20

...BRCA1 and BRCA2 (BRCA) gene mutations. In a sample of Black women with early onset breast cancer, we evaluated BRCA muta...

Hereditary breast cancer in the Han Chinese population.

Cao(Wenming),Wang(Xiaojia),Li(Ji-Cheng) J Epidemiol 2013-04-22

...BRCA1 and BRCA2 are the 2 most important susceptibility genes. They have a relatively low mutation rate, and the most fr...

BRCA1 mRNA expression as a predictive and prognostic marker in advanced esophag…

Gao(Yong),Zhu(Jing),Zhang(Xiaohui),Wu(Qingqu… PLoS One 2013-07-05

...BRCA1) expression has been found to switch the response to cisplatin- or paclitaxel-based chemotherapy. It remains uncle...

VEGF, HIF-1α expression and MVD as an angiogenic network in familial breast can…

Saponaro(Concetta),Malfettone(Andrea),Ranier… PLoS One 2013-07-05

...BRCA1 carrier cancers, but little has been reported about angiogenesis in BRCA1-2 carrier and BRCAX breast cancers. In t...

Factors affecting response of chemotherapy in women with ovarian cancer.

Lubin(J),Markowska(A),Knapp(P) Eur J Gynaecol Oncol 2013-04-16

...BRCA1 protein, TP53 protein, YY1 protein, multidrug resistance protein, and interleukin-8.

Coffee and caffeine intake and breast cancer risk: an updated dose-response met…

Jiang(Wenjie),Wu(Yili),Jiang(Xiubo) Gynecol Oncol 2013-06-28

...BRCA1 mutation carriers (RR=0.69, P<0.01). A linear dose-response relationship was found for breast cancer risk with cof...

[New genetic tests and their clinical utility for cancer screening].

Probst-Hensch(Nicole M),Brand(Angela) Ther Umsch 2013-07-09

...BRCA1 and BRCA2 mutations dramatically. In recent years, the research has moved towards the decoding of the genetic caus...

Genotyping by induced Förster Resonance Energy Transfer(iFRET) mechanism and si…

Masojć(Bartłomiej),Górski(Bohdan),van de Wet… Hum Mutat 2013-09-06

...BRCA1, a singular polymorphism in CCND1 and somatic mutations in KRAS and BRAF genes. The validation set consisted of 14...

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