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TP53 BRCA1 CRISPR single-cell cancer

Lee(Si Young),Rozenzhak(Sophie),Russell(Paul) Mol Cell Biol 2013-07-30

...BRCA1) C-terminal (BRCT) domains. Brc1 prevents the collapse of stalled replication forks; however, it is unknown whethe...

Shin(Soon Young),Kim(Chang Gun),Lee(Young Ha… BMB Rep 2013-08-19

...BRCA1 gene. However, only a few studies have reported on the mechanism underlying the regulation of BRCA1 expression in ...

Tu(Zhigang),Zhuang(Xinying),Yao(Yong-Gang),Z… Mol Cell Biol 2013-05-29

...BRCA1 from chromatin and BRCA1 knockdown itself drive senescence by promoting formation of senescence-associated heteroc...

Bojesen(Stig E),Pooley(Karen A),Johnatty(Sha… Nat Genet 2013-05-21

...BRCA1 mutation carrier (n = 11,705) cancer cases and controls. Leukocyte telomere measurements were also available for 5...

Stevens(Kristen N),Vachon(Celine M),Couch(Fe… Cancer Res 2013-06-25

...BRCA1 and BRCA2 breast cancer susceptibility genes have been associated with up to 15% of TNBC, and TNBC accounts for 70...

Tea(Muy-Kheng M),Weghofer(Andrea),Wagner(Kla… Maturitas 2013-12-17

...BRCA1/2 carriers and healthy controls (p<0.001). In addition, BRCA1/2 carriers indicated a trend toward shorter reproduc...

Gaudet(Mia M),Kuchenbaecker(Karoline B),Vija… PLoS Genet 2013-06-13

...BRCA1/2 were genotyped and available for analysis. We replicated previously reported breast cancer susceptibility allele...

Couch(Fergus J),Wang(Xianshu),McGuffog(Lesle… PLoS Genet 2013-06-13

...BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7 ×...

Ingham(Sarah Louise),Warwick(Jane),Buchan(Ia… J Med Genet 2013-12-09

...BRCA1/2 genes confer ovarian, alongside breast, cancer risk. We examined the risk of developing ovarian cancer in BRCA1/...

Satija(Yatendra Kumar),Bhardwaj(Abhishek),Da… Int J Cancer 2013-12-09

...BRCA1 and VHL RING type ligases function as tumor suppressors and play an important role in DNA repair and hypoxia respo...

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