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TP53 BRCA1 CRISPR single-cell cancer

Shimada(Mikio),Hirayama(Ryoichi),Komatsu(Ken… Int J Radiat Oncol Biol Phys 2013-06-26

...Brca1-deficient cells. Because NBS1/BRCA1 is implicated in monoubiquitination of γ-tubulin, we subsequently tested wheth...

Powell(C B),Swisher(E M),Cass(I),McLennan(J)… Gynecol Oncol 2013-06-11

The reported incidence of neoplasia identified at the time of risk-reducing salpingo-oophorectomy (RRSO) in germline BRC...

Ternovoĭ(S K),Matkhev(S),Meladze(N V),Solopo… Vestn Rentgenol Radiol 2013-05-14

...BRCA1/2 gene mutations was determined in patients with BC identified during the mammographic screening. A relationship w...

Madjd(Zahra),Karimi(Adel),Molanae(Saadat),As… Cell J 2013-03-20

...BRCA1 mutation carriers suggest that BRCA1 may function as a stem-cell regulator.,In the present experimental study we e...

Kass(Elizabeth M),Helgadottir(Hildur R),Chen… Proc Natl Acad Sci U S A 2013-06-11

...Brca1, a significant reduction in HDR was detected, showing that BRCA1 is critical for HDR in somatic cell types. Consis...

Zhang(Jian),Shi(Yuhao),Lalonde(Emilie),Li(Li… BMC Cancer 2013-09-16

...BRCA1 S1841R mutation.,We observed loss of heterozygosity in the BRCA1 mutation in the primary and subsequent tumors, an...

Sudo(Hideki),Yamada(Katsuhisa),Iwasaki(Koji)… PLoS One 2013-09-10

...Brca1, Cdc25, Gadd45, Hus1, Ppm1D, Rad 9, Tp53, and Cyclin D1. Both p27(Kip1) and p53 protein expression was upregulated...

Huntoon(Catherine J),Flatten(Karen S),Wahner… Cancer Res 2013-08-30

...BRCA1-depleted cells to cisplatin, topotecan, and veliparib beyond the potent sensitization already caused by their defi...

Tiseo(M),Bordi(P),Bortesi(B),Boni(L),Boni(C)… Br J Cancer 2013-07-15

...BRCA1 expression and ERCC1/XPD/XRCC1-3 gene polymorphisms on outcomes of patients was examined.,Patients were randomised...

Sitzmann(James V),Wiebke(Eric A) JAMA Surg 2013-05-23

...BRCA1/2 carriers after RRBSO. The source of intraperitoneal cancer in BRCA1/2 carriers after risk-reducing salpingo-ooph...

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