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TP53 BRCA1 CRISPR single-cell cancer

Margalit(Ofer),Wang(Dingzhi),Dubois(Raymond … Cancer Prev Res (Phila) 2013-03-21

...BRCA1 tumor-suppressor gene regulate aromatase expression. In this issue of the journal (beginning on p. 1183), Subbaram...

Abkevich(V),Timms(K M),Hennessy(B T),Potter(… Br J Cancer 2013-04-01

Defects in BRCA1, BRCA2, and other members of the homologous recombination pathway have potential therapeutic relevance ...

Salem(Ahmed F),Howell(Anthony),Sartini(Marin… Cell Cycle 2013-04-30

...BRCA1 expression in human hTERT-immortalized fibroblasts (shBRCA1) using an shRNA lentiviral approach. As expected, shBR...

Martinez-Outschoorn(Ubaldo E),Balliet(Renee … Cell Cycle 2013-04-30

...BRCA1-null ovarian cancer cells on adjacent tumor-associated stromal fibroblasts. Our results directly show that BRCA1-n...

Ingham(S L),Warwick(J),Byers(H),Lalloo(F),Ne… Clin Genet 2013-12-30

...BRCA1/BRCA2 mutations. BRCA1/2 mutation carriers identified through the Manchester genetics centre between 1996 and 2011...

Jaspers(Janneke E),Kersbergen(Ariena),Boon(U… Cancer Discov 2013-06-20

...BRCA1-associated cancers. We previously reported that BRCA1-deficient mouse mammary tumors may acquire resistance to the...

Lok(Benjamin H),Powell(Simon N) Clin Cancer Res 2013-05-20

...BRCA1)-BRCA2 pathway of homologous recombination. Biochemical studies also showed significant differences between yeast ...

Mohammed(Ahmed El Sayed),Eguchi(Hidetaka),Wa… Exp Lung Res 2013-03-14

...BRCA1, FRAP1, and RRM1, were subjected to a linear regression analysis using 12 NSCLC cell lines including 6 additional ...

Iqbal(J),Ragone(A),Lubinski(J),Lynch(H T),Mo… Br J Cancer 2013-02-15

Germline mutations in BRCA1 and BRCA2 predispose to pancreatic cancer. We estimated the incidence of pancreatic cancer i...

Blank(Jonathan L),Liu(Xiaozhen J),Cosmopoulo… Cancer Res 2013-02-27

...BRCA1/BRCA2, transcription-coupled repair, and base excision repair seemed to be important for MLN4924 lethality. In con...

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