...BRCA1) and regulates BRCA1-mediated transcription via modulation of promoter occupancy and histone modification. We used...
...BRCA1, ATR and Chk1 in PCBL treated cells demonstrated the DNA damaging property of PCBL. Effector molecules of apoptosi...
...BRCA1 intragenic microsatellite markers and two markers surrounding the BRCA1 locus. The segregation analysis showed one...
Germline mutations in BRCA1 and BRCA2 account for ~30 % of inherited breast cancer. RAD51C was reported as an additional...
...brca1 complex. H2A.Z exchange also restricts single-stranded DNA production by nucleases and is required for loading of ...
Germline mutations of human breast cancer-associated gene 1 (BRCA1) predispose women to breast and ovarian cancers. In m...
...BRCA1/2 test results with young children and advice for parents considering disclosure and for genetic counselors. Inter...
...BRCA1 and BRCA2 genes. The prevalence of germline mutations in theBRCA1 and BRCA2 genes varies among ethnic groups. The ...
BRCA1 functions as a tumor suppressor gene and germline and somatic mutations in this gene have been shown to be associa...
...BRCA1 or BRCA2 (BRCA1/2) mutations face difficult decisions about managing their high risks of breast and ovarian cancer...
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