...BRCA1/2 genes. The majority (76 %) of high-risk girls perceive themselves to be at increased risk for breast cancer, com...
...BRCA1 can be found in the same protein complex, which is reduced by lapatinib. Interestingly, lapatinib also increases c...
...BRCA1 carboxyl-terminal (BRCT) domain is frequently present in proteins involved in the DDR, can exist either as an indi...
...BRCA1-related cancers, needs to be confirmed in large randomized trials. Bevacizumab combined with neoadjuvant chemother...
...BRCA1 gene expression, and Western blot was performed to assay the expression of BRCA1 protein.,BRCA1 showed hypomethyla...
...BRCA1, CCND2, CDH1, ESR1, GSTP1, HIN1, P16, RARβ, RASSF1, SFRP1 and TWIST) to measure the degree of methylation would le...
...BRCA1), further studies demonstrate that Slug-as well as Snail-directly represses BRCA1 expression by recruiting the chr...
...BRCA1-mutated and therefore patients with this type of tumour are at a potentially elevated risk of ipsilateral or contr...
...BRCA1 mutations is driving clinical research into the use of DNA-damaging agents such as platinums, as well as of potent...
...BRCA1 mutation, and newer targeted agents such as anti-angiogenic treatment with bevacizumab or anti-epidermal growth fa...
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