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Conservation of function and primary structure in the BRCA1-associated RING d...

Ayi(T C),Tsan(J T),Hwang(L Y),Bowcock(A M)... Oncogene 1998-11-19

...BARD1, a protein that interacts with BRCA1 to form a stable heterodimer. BARD1 is structurally similar to BRCA1 in that ...

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are in...

Scully(R),Chen(J),Ochs(R L),Keegan(K),Hoek... Cell 1997-09-08

...BARD1, and Rad51 accumulated, focally, on PCNA+ replication structures, implying an interaction of BRCA1/BARD1/Rad51 con...

Identification of a RING protein that can interact in vivo with the BRCA1 gen...

Wu(L C),Wang(Z W),Tsan(J T),Spillman(M A),... Nat Genet 1997-01-02

...BARD1) protein contains an N-terminal RING motif, three tandem ankyrin repeats, and a C-terminal sequence with significa...

Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete n...

Jin(Y),Xu(X L),Yang(M C),Wei(F),Ayi(T C),B... Proc Natl Acad Sci U S A 1997-12-04

...BARD1. Here we show that the steady-state levels of BARD1, unlike those of BRCA1, remain relatively constant during cell...

Frequent incidence of BARD1-truncating mutations in germline DNA from triple-...

De Brakeleer(S),De Grève(J),Desmedt(C),Jor... Clin Genet 0000-00-00

...BARD1, a BRCA1 interacting protein, in families at high risk for BC. In this study, we have analyzed germline DNA from 6...

Multimodal approach to explore the pathogenicity of BARD1, ARG 658 CYS, and I...

Choudhary(Rajan Kumar),Vikrant,Siddiqui(Qu... J Biomol Struct Dyn 0000-00-00

...BARD1BRCT in the DNA repair mechanism, in silico, in vitro, and biophysical approach were applied to characterize BARD1 ...

Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes ...

Caminsky(Natasha G),Mucaki(Eliseos J),Perr... Hum Mutat 0000-00-00

...BARD1, BRCA1, BRCA2, CDH1, CHEK2, EPCAM, MLH1, MRE11A, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, PTEN, RAD51B, STK11, TP53, a...

Identification of germline alterations in breast cancer predisposition genes ...

Ng(P S),Wen(W X),Fadlullah(M Z H),Yoon(S Y... Clin Genet 0000-00-00

...BARD1. Our study shows that BRCA1 and BRCA2 account for the majority of genetic predisposition to breast cancer in our c...

Multigene testing of moderate-risk genes: be mindful of the missense.

Young(E L),Feng(B J),Stark(A W),Damiola(F)... J Med Genet 0000-00-00

...BARD1 in 1297 cases of early-onset breast cancer and 1121 controls via scores from Align-Grantham Variation Grantham Dev...

New concepts on BARD1: Regulator of BRCA pathways and beyond.

Irminger-Finger(Irmgard),Ratajska(Magda),P... Int J Biochem Cell Biol 0000-00-00

...BARD1 was closely linked to research on BRCA1, the breast cancer predisposition gene. The co-expression of BARD1 and BRC...

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