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Implications of BRCA1 and BRCA2 mutations for the efficacy of paclitaxel monoth…

Tan(David S P),Yap(Timothy A),Hutka(Margaret… Eur J Cancer 2013-05-28

...BRCA1 and BRCA2 (BRCA1/2)-mutated ovarian cancers (BMOC) are exquisitely sensitive to platinum-salts, but resistant to m...

Risk of asynchronous contralateral breast cancer in noncarriers of BRCA1 and BR…

Reiner(Anne S),John(Esther M),Brooks(Jennife… J Clin Oncol 2013-03-11

...BRCA1 and BRCA2 mutations.,From our population-based case-control study comparing women with CBC to women with unilatera...

TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness.

Shan(Jingxuan),Dsouza(Shoba P),Bakhru(Sasha)… Cancer Res 2013-06-24

...BRCA1 expression were inversely correlated. Notably, we found that TNRC9 bound to both the BRCA1 promoter and the cAMP-r...

Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor cha…

Carraro(Dirce Maria),Koike Folgueira(Maria A… PLoS One 2013-08-27

Germline mutations in BRCA1, BRCA2 and TP53 genes have been identified as one of the most important disease-causing issu...

BRCA1 protein expression and its correlation with ER/PR status in sporadic and …

Ashraf(M),Jha(J K),Mukherjee(N),Panda(C K),N… J Indian Med Assoc 2013-05-02

BRCA1 gene expression in familial breast cancer is mainly focused on mutational analysis. However in sporadic cancers BR...

Predicting high risk disease using serum and DNA biomarkers.

Vesprini(Danny),Liu(Stanley),Nam(Robert) Curr Opin Urol 2013-09-24

...BRCA1 and BRCA2, Phosphatase and tensin homolog, cellular myelocytomatosis oncogene and NKX3.1 may predict for aggressiv...

Design, synthesis, and biological evaluation of a series of benzo[de][1,7]napht…

Ye(Na),Chen(Chuan-Huizi),Chen(Tiantian),Song… J Med Chem 2013-06-11

...BRCA1-deficient MDA-MB-436 cells (CC50 < 0.26 nM). Mechanistic studies revealed that the new PARP1 inhibitors significan...

Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cas…

Stavropoulou(Alexandra V),Fostira(Florentia)… PLoS One 2013-12-27

...BRCA1 account for 63% of all mutations detected in both BRCA1 and BRCA2 genes. This study aimed to determine the prevale...

The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an…

Segev(Yakir),Iqbal(Javaid),Lubinski(Jan),Gro… Gynecol Oncol 2013-08-19

...BRCA1 or the BRCA2 gene.,We followed 4456 women with a BRCA1 or a BRCA2 mutation for incident cases of endometrial cance...

Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activ…

Pérez-de-Puig(I),Martín(A),Gorina(R),de la R… Neuroscience 2013-12-17

...BRCA1) associated C-terminal helicase 1 (Bach-1). While Nrf2 is activated after ischemia and drugs promoting Nrf2 activa...

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