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Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation.

Finch(Amy),Valentini(Adriana),Greenblatt(Ell… Fertil Steril 2013-07-02

To evaluate the impact of carrying a BRCA1 or BRCA2 mutation on the probability of experiencing premature natural menopa...

Proposed roadmap to stepwise integration of genetics in family medicine and cli…

Houwink(Elisa Jf),Sollie(Annet W),Numans(Mat… Clin Transl Med 2013-03-19

...BRCA1 mutation as an example.

BRCA1 is a novel target to improve endothelial dysfunction and retard atheroscl…

Singh(Krishna K),Shukla(Praphulla C),Quan(Ad… J Thorac Cardiovasc Surg 2013-11-08

...BRCA1 is basally expressed in endothelial cells. BRCA1 overexpression protected and BRCA1 silencing exaggerated inflamma...

BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionall…

Stordal(Britta),Timms(Kirsten),Farrelly(Ange… Mol Oncol 2013-12-23

...BRCA1/2 genes were sequenced in 41 ovarian cell lines, mRNA expression of BRCA1/2 and gene methylation status of BRCA1 w...

Excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive …

Adank(Muriel A),Verhoef(Senno),Oldenburg(Rog… Eur J Cancer 2013-07-05

...BRCA1/2 breast cancer setting.,Cancer incidences were compared between first degree relatives of 107 familial breast can...

Expression of human BRCA1Δ17-19 alternative splicing variant with a truncated B…

Sevcik(Jan),Falk(Martin),Macurek(Libor),Klei… Cell Signal 2013-10-18

...BRCA1 pre-mRNA can give rise to BRCA1 protein isoforms that possess dramatically altered biological activities compared ...

Tumours associated with BAP1 mutations.

Murali(Rajmohan),Wiesner(Thomas),Scolyer(Ric… Pathology 2013-07-11

...BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that ...

Association between the c.*229C>T polymorphism of the topoisomerase IIβ binding…

Forma(Ewa),Brzeziańska(Ewa),Krześlak(Anna),C… Mol Biol Rep 2013-09-13

...BRCA1 prompted us to investigate whether alterations in the TopBP1 gene can influence the risk of breast cancer. The aim...

Role of DNA repair and cell cycle control genes in ovarian cancer susceptibilit…

Mohamed(Faten Zahran),Hussien(Yousry Mostafa… Mol Biol Rep 2013-09-13

...BRCA1 and BRCA2) are probably responsible for only 40% of the excess familial ovarian cancer risks, suggesting that othe...

The ectopic expression of BRCA1 is associated with genesis, progression, and pr…

Zhang(Qingli),Zhang(Qinghui),Cong(Hua),Zhang… Diagn Pathol 2013-05-10

...BRCA1 protein in the young group was higher than that in the old group. BRCA1 expression was positively correlated with ...

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