...BRCA1) in cardiac tissue and fibroblast, which subsequently activate the transcription factor Nuclear factor (erythroid-...
The pathogenic sequelae of BRCA1 mutation in human and mouse cells are mitigated by concomitant deletion of 53BP1, which...
...BRCA1, mutant BRCA1, BRCA1 knocked-down and BRCA1 overexpressed breast cancer cells were treated with the cucurbitacin B...
...BRCA1, COX2, ERCC1, IGFBP3, RRM1, and TUBB3), and stemness-related genes (CD133, OCT4, and SLUG) in two cellular models ...
...BRCA1, FANCD2, RAD51, and γ-H2AX.,Four cell lines (25%) showed an impaired RAD51 foci-forming ability in response to cis...
BRCA1 function is inactivated through BRCA1 promoter methylation in a substantial number of triple-negative breast cance...
...BRCA1 promoter was detected in 78 (56%) of the 139 tumors. Chi-square analysis indicated that BRCA1 promoter methylation...
...BRCA1- and BRCA2-mutated tumors were significantly correlated to specific subtypes. In this chapter, we will review the ...
...BRCA1 and LMO4, PFS was 19 months whereas it was not reached in those with low BRCA1 and high LMO4 mRNA levels (p = 0.04...
...BRCA1, MRE11, Rad51, and ATM, but not BRCA2, declines in single mouse and human oocytes. In Brca1-deficient mice, reprod...
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