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3,3'-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activa…

Yao(Zhengwei),Hu(Wei),Yin(Shan),Huang(Zhen),… Pharmacol Res 2013-09-10

...BRCA1) in cardiac tissue and fibroblast, which subsequently activate the transcription factor Nuclear factor (erythroid-...

Acetylation limits 53BP1 association with damaged chromatin to promote homologo…

Tang(Jiangbo),Cho(Nam Woo),Cui(Gaofeng),Mani… Nat Struct Mol Biol 2013-05-03

The pathogenic sequelae of BRCA1 mutation in human and mouse cells are mitigated by concomitant deletion of 53BP1, which...

The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells.

Promkan(Moltira),Dakeng(Sumana),Chakrabarty(… PLoS One 2013-08-26

...BRCA1, mutant BRCA1, BRCA1 knocked-down and BRCA1 overexpressed breast cancer cells were treated with the cucurbitacin B...

Specific Biomarkers Are Associated with Docetaxeland Gemcitabine-Resistant NSCL…

Pasini(Alice),Paganelli(Giulia),Tesei(Anna),… Transl Oncol 2013-02-12

...BRCA1, COX2, ERCC1, IGFBP3, RRM1, and TUBB3), and stemness-related genes (CD133, OCT4, and SLUG) in two cellular models ...

Detection of impaired homologous recombination repair in NSCLC cells and tissue…

Birkelbach(Moritz),Ferraiolo(Natalie),Gheorg… J Thorac Oncol 2013-07-30

...BRCA1, FANCD2, RAD51, and γ-H2AX.,Four cell lines (25%) showed an impaired RAD51 foci-forming ability in response to cis...

Promoter methylation of BRCA1 in triple-negative breast cancer predicts sensiti…

Xu(Y),Diao(L),Chen(Y),Liu(Y),Wang(C),Ouyang(… Ann Oncol 2013-11-18

BRCA1 function is inactivated through BRCA1 promoter methylation in a substantial number of triple-negative breast cance...

Methylation of BRCA1 promoter region is associated with unfavorable prognosis i…

Hsu(Nicholas C),Huang(Ya-Fang),Yokoyama(Kazu… PLoS One 2013-08-20

...BRCA1 promoter was detected in 78 (56%) of the 139 tumors. Chi-square analysis indicated that BRCA1 promoter methylation...

Nonfamilial breast cancer subtypes.

Ringnér(Markus),Staaf(Johan),Jönsson(Göran) Methods Mol Biol 2013-07-29

...BRCA1- and BRCA2-mutated tumors were significantly correlated to specific subtypes. In this chapter, we will review the ...

BRCA1, LMO4, and CtIP mRNA expression in erlotinib-treated non-small-cell lung …

Karachaliou(Niki),Costa(Carlota),Gimenez-Cap… J Thorac Oncol 2013-07-30

...BRCA1 and LMO4, PFS was 19 months whereas it was not reached in those with low BRCA1 and high LMO4 mRNA levels (p = 0.04...

Impairment of BRCA1-related DNA double-strand break repair leads to ovarian agi…

Titus(Shiny),Li(Fang),Stobezki(Robert),Akula… Sci Transl Med 2013-07-26

...BRCA1, MRE11, Rad51, and ATM, but not BRCA2, declines in single mouse and human oocytes. In Brca1-deficient mice, reprod...

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