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Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer …

Gracia-Aznarez(Francisco Javier),Fernandez(V… PLoS One 2013-09-06

The identification of the two most prevalent susceptibility genes in breast cancer, BRCA1 and BRCA2, was the beginning o...

HIF-1α overexpression in ductal carcinoma in situ of the breast in BRCA1 and BR…

van der Groep(Petra),van Diest(Paul J),Smold… PLoS One 2013-08-05

...BRCA1, 16 BRCA2 and 77 non-BRCA mutation-related cases. HIF-1α expression was detected in 63% of BRCA1 and 62% of BRCA2 ...

Germline BRCA mutations are associated with higher risk of nodal involvement, d…

Castro(Elena),Goh(Chee),Olmos(David),Saunder… J Clin Oncol 2013-07-01

...BRCA1 and BRCA2 (BRCA1/2) mutations and the prognostic value of those mutations on prostate cancer (PCa) outcomes.,This ...

A case of synchronous double primary breast carcinoma and osteosarcoma: Mismatc…

Ahmed(Hytham),Salama(Asmaa),Salem(Salem Eid)… Am J Case Rep 2013-04-10

...BRCA1 gene mutations were detected in the breast tumor, with reduced mRNA expression of BRCA1&2. ERCC1, MLH1 and MSH2, e...

Evaluating the performance of the breast cancer genetic risk models BOADICEA, I…

Fischer(Christine),Kuchenbäcker(Karoline),En… J Med Genet 2013-12-09

...BRCA1/2 mutation carrier probabilities, have never been comparatively evaluated in a large sample from central Europe. A...

Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmuno…

Al-Ejeh(Fares),Shi(Wei),Miranda(Mariska),Sim… J Nucl Med 2013-08-01

...BRCA1 inactivation in TNBC has rationalized clinical trials of poly(adenosine diphosphate ribose) polymerase (PARP) inhi...

PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-e…

Chatterjee(Payel),Choudhary(Gaurav S),Sharma… PLoS One 2013-09-23

...BRCA1 and BRCA2 that impair homologous recombination. However, since many tumors, including prostate cancer (PCa) rarely...

Antineoplastic effects of α-santalol on estrogen receptor-positive and estrogen…

Santha(Sreevidya),Bommareddy(Ajay),Rule(Brit… PLoS One 2013-09-27

...BRCA1, Chk1, G2/M regulatory cyclins, Cyclin dependent kinases (CDKs), Cell division cycle 25B (Cdc25B), Cdc25C and Ser-...

Genetic predisposition syndromes and their management.

Euhus(David M),Robinson(Linda) Surg Clin North Am 2013-04-22

...BRCA1, BRCA2, and TP53, more than a dozen breast cancer susceptibility genes have been identified. Recognizing affected ...

Platform comparisons for identification of breast cancers with a BRCA-like copy…

Schouten(Philip C),van Dyk(Ewald),Braaf(Lind… Breast Cancer Res Treat 2013-12-30

...BRCA1 and -2 mutations, designated 'BRCA1 and -2-like' tumours, respectively. The classifiers are used in clinical genet...

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