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What factors may influence psychological well being at three months and one yea…

Bosch(Nina),Junyent(Núria),Gadea(Neus),Brune… Breast 2013-05-01

...BRCA1/2 genetic result. We analyzed potential predictors for pathological anxiety and variables associated to the variat...

Are we being overly cautious? A qualitative inquiry into the experiences and pe…

Zilliacus(E),Meiser(B),Gleeson(M),Watts(K),T… Support Care Cancer 2013-03-27

...BRCA1/2 mutation carriers, have a high risk of ovarian cancer and metachronous breast cancer. Treatment-focused genetic ...

Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP5…

Schulz(Eduard),Valentin(Angelika),Ulz(Peter)… J Med Genet 2013-01-07

...BRCA1 (c.3112G→T, c.5251C→T), one BRCA2 (c.4027A→G), two BARD1 (C557S) and four TP53 germline mutations (g.18508_18761de...

Estimating survival rates after ovarian cancer among women tested for BRCA1 and…

Narod(S A),Moody(J R K),Rosen(B),Fan(I),Risc… Clin Genet 2013-08-27

...BRCA1 or BRCA2 mutations have better survival than women with ovarian cancer and no mutation. Potential reasons for this...

BRCAness: finding the Achilles heel in ovarian cancer.

Rigakos(Georgios),Razis(Evangelia) Oncologist 2013-02-07

...BRCA1/2 are the fundamental defects in hereditary ovarian cancer that expresses a distinct phenotype of high response ra...

Haplotype analysis of two recurrent genomic rearrangements in the BRCA1 gene su…

Pertesi(M),Konstantopoulou(I),Yannoukakos(D) Clin Genet 2013-08-22

...BRCA1 gene in Greek breast cancer patients. They have been reported previously six and three times, respectively, in unr...

Insights into the targeted elimination of BRCA1-defective cancer stem cells.

Somasundaram(Veena),Srinivas(Priya) Med Res Rev 2013-05-09

...BRCA1-defective tumor progression, phenotype of BRCA1-defective cancers, role of BRCA1 in other cancers and finally at w...

An ELISA-based high throughput protein truncation test for inherited breast can…

Lim(Mark J),Foster(Gabriel J),Gite(Sadanand)… Breast Cancer Res 2013-02-12

...BRCA1/2 analysis.,Segments of exons 11 of BRCA1/2 open reading frames were PCR amplified from either blood derived genom...

Advantage of high-resolution melting curve analysis over conformation-sensitive…

de Juan Jiménez(Inmaculada),Cardeñosa(Eva Es… Clin Chim Acta 2013-08-07

...BRCA1 and BRCA2 (BRCAs) genes is a time-consuming and costly procedure that demands faster and cheaper alternative metho...

The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation c…

Sandhu(Shahneen K),Schelman(William R),Wildi… Lancet Oncol 2013-09-30

...BRCA1 and BRCA2 mutation carriers, received niraparib daily at ten escalating doses from 30 mg to 400 mg in a 21-day cyc...

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