Women with mutations in BRCA1 or BRCA2 are at high risk of developing breast cancer and, in British Columbia, Canada, ar...
...BRCA1-associated protein 1 (BAP1), not only in cases of familial mesothelioma, but also BAP1 deletion in sporadic MM. Pr...
...BRCA1 and BRCA2.,BRCA1-mutated (but not BRCA2-mutated) ovarian carcinomas had significantly higher 53BP1 protein express...
This study examines the process of communicating BRCA1/2 genetic test results to family members, and the factors influen...
...BRCA1 E3 ligase in these cellular functions is poorly understood. We present data showing that BRCA1 ubiquitinates G2/M ...
...BRCA1/BARD1 complexes at sites of DNA damage; and defines one of the mechanisms by which 53BP1 causes chromosomal abnorm...
...BRCA1 and BRCA2 (BRCA) gene mutations. In a sample of Black women with early onset breast cancer, we evaluated BRCA muta...
...BRCA1 and BRCA2 genes combined with a variant prioritization pipeline, designed to minimize the number of false-positive...
...BRCA1 and BRCA2 are the 2 most important susceptibility genes. They have a relatively low mutation rate, and the most fr...
...BRCA1-associated protein 1 (BAP1), which contains the ubiquitin C-terminal hydrolase (UCH) domain. Both the UCH- and ASX...
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