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Cost-effectiveness of MRI for breast cancer screening in BRCA1/2 mutation carri…

Pataky(Reka),Armstrong(Linlea),Chia(Stephen)… BMC Cancer 2013-11-26

Women with mutations in BRCA1 or BRCA2 are at high risk of developing breast cancer and, in British Columbia, Canada, ar...

Challenges and controversies in the diagnosis of malignant mesothelioma: Part 2…

Henderson(Douglas W),Reid(Glen),Kao(Steven C… J Clin Pathol 2013-11-12

...BRCA1-associated protein 1 (BAP1), not only in cases of familial mesothelioma, but also BAP1 deletion in sporadic MM. Pr...

53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to g…

Pennington(Kathryn P),Wickramanayake(Anneka)… Gynecol Oncol 2013-06-24

...BRCA1 and BRCA2.,BRCA1-mutated (but not BRCA2-mutated) ovarian carcinomas had significantly higher 53BP1 protein express...

Family communication following BRCA1/2 genetic testing: a close look at the pro…

Lafrenière(Darquise),Bouchard(Karine),Godard… J Genet Couns 2013-12-09

This study examines the process of communicating BRCA1/2 genetic test results to family members, and the factors influen...

BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degra…

Shabbeer(S),Omer(D),Berneman(D),Weitzman(O),… Oncogene 2013-12-23

...BRCA1 E3 ligase in these cellular functions is poorly understood. We present data showing that BRCA1 ubiquitinates G2/M ...

53BP1 regulates DSB repair using Rif1 to control 5' end resection.

Zimmermann(Michal),Lottersberger(Francisca),… Science 2013-02-20

...BRCA1/BARD1 complexes at sites of DNA damage; and defines one of the mechanisms by which 53BP1 causes chromosomal abnorm...

Early onset breast cancer in a registry-based sample of African-american women:…

Pal(Tuya),Bonner(Devon),Kim(Jongphil),Montei… Breast J 2013-09-20

...BRCA1 and BRCA2 (BRCA) gene mutations. In a sample of Black women with early onset breast cancer, we evaluated BRCA muta...

Nonoptical massive parallel DNA sequencing of BRCA1 and BRCA2 genes in a diagno…

Costa(José Luis),Sousa(Sónia),Justino(Ana),K… Hum Mutat 2013-09-06

...BRCA1 and BRCA2 genes combined with a variant prioritization pipeline, designed to minimize the number of false-positive...

Hereditary breast cancer in the Han Chinese population.

Cao(Wenming),Wang(Xiaojia),Li(Ji-Cheng) J Epidemiol 2013-04-22

...BRCA1 and BRCA2 are the 2 most important susceptibility genes. They have a relatively low mutation rate, and the most fr...

Retracted: Histone H2B ubquitination regulates retinoic acid signaling through …

Lee(Sang-Wang),Youn(Hyesook),Kim(Eun-Joo),Um… Mol Cell 2013-11-11

...BRCA1-associated protein 1 (BAP1), which contains the ubiquitin C-terminal hydrolase (UCH) domain. Both the UCH- and ASX...

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