Here, we show for the first time, that the familial breast/ovarian cancer susceptibility gene BRCA1 activates the Notch ...
...BRCA1 and 53BP1 and compromised cell survival after ionizing radiation. We propose that USP34 promotes a feed-forward lo...
We tested the hypothesis that BRCA1/2 mutation carriers with ovarian cancer are at higher risk of carboplatin hypersensi...
...BRCA1/2 mutations.,Nearly 25% of the participants were classified as being at high risk of carrying a BRCA1/2 mutation b...
...BRCA1/2 genetic counseling and testing for managing hereditary breast and ovarian cancer risk; however, BRCA1/2 genetic ...
...BRCA1 and BRCA2 mutations was performed in 12 of 28 young patients and mutations were found in 25% of them. Moreover, yo...
...BRCA1/BRCA2 mutation carriers. Bilateral prophylactic salpingo-oophorectomy is recommended for BRCA1/ BRCA2 carriers: wo...
Although BRCA1/2 genetic testing is discouraged in minors, mothers may disclose their own results to their children. Fac...
...BRCA1-associated protein-1 (BAP1). Recently, germ-line mutations in BAP1, the gene encoding a tumor suppressing deubiqui...
...BRCA1 and BRCA2 mutation carriers are at increased risk of clinically significant prostate cancer and may benefit from s...
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