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The role of BRCA1 in homologous recombination repair in response to replication…

Zhang(Junran) Cell Biosci 2013-03-19

...BRCA1) predispose women to breast and ovarian cancers. Although BRCA1 is involved in many important biological processes...

Breast cancer and genetics.

Boeri(L),Canzonieri(C),Cagioni(C),Ornati(F),… J Ultrasound 2013-02-12

...BRCA1 gene was identified as the first gene responsible for hereditary forms of breast cancer and subsequently BRCA2. In...

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid…

Warmoes(Marc),Jaspers(Janneke E),Xu(Guotai),… Mol Cell Proteomics 2013-12-09

...Brca1) gene. The proteome of cisplatin-sensitive BRCA1-deficient mammary tumors was compared with that of cisplatin-resi...

Risk of pancreatic cancer in breast cancer families from the breast cancer fami…

Mocci(Evelina),Milne(Roger L),Méndez-Villami… Cancer Epidemiol Biomarkers P… 2013-11-07

...BRCA1 and/or BRCA2 were eligible. Families were divided into four classes: BRCA1, BRCA2, BRCAX with ≥2 breast cancer dia...

Comparative in vitro and in silico analyses of variants in splicing regions of …

Colombo(Mara),De Vecchi(Giovanna),Caleca(Lau… PLoS One 2013-09-27

...BRCA1 and BRCA2 splice sites were characterized by transcripts analysis. These results were used to evaluate the ability...

Detection of promoter methylation of tumor suppressor genes in serum DNA of bre…

Sturgeon(Susan R),Balasubramanian(Raji),Scha… Epigenetics 2013-04-16

...BRCA1, CCND2, CDH1, ESR1, GSTP1, HIN1, P16, RARβ, RASSF1, SFRP1 and TWIST) to measure the degree of methylation would le...

Neoadjuvant treatment for HER-2-positive and triple-negative breast cancers.

Sousa(B),Cardoso(F) Ann Oncol 2013-04-26

...BRCA1-related cancers, needs to be confirmed in large randomized trials. Bevacizumab combined with neoadjuvant chemother...

Charting the landscape of tandem BRCT domain-mediated protein interactions.

Woods(Nicholas T),Mesquita(Rafael D),Sweet(M… Sci Signal 2013-02-01

...BRCA1 carboxyl-terminal (BRCT) domain is frequently present in proteins involved in the DDR, can exist either as an indi...

Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation…

Choi(Jae Duk),Park(Mi Ae),Lee(Jong-Soo) Nucleic Acids Res 2013-02-22

...BRCA1) and regulates BRCA1-mediated transcription via modulation of promoter occupancy and histone modification. We used...

What factors may influence psychological well being at three months and one yea…

Bosch(Nina),Junyent(Núria),Gadea(Neus),Brune… Breast 2013-05-01

...BRCA1/2 genetic result. We analyzed potential predictors for pathological anxiety and variables associated to the variat...

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