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Exome and deep sequencing of clinically aggressive neuroblastoma reveal somat...

Lasorsa(Vito Alessandro),Formicola(Daniela... Oncotarget 0000-00-00

...BARD1, CHEK2 and AXIN2 were enriched in rare, potentially pathogenic, germline variants.In summary, whole exome and deep...

Frequency of germline DNA genetic findings in an unselected prospective cohor...

González-Rivera(Milagros),Lobo(Miriam),Lóp... Breast Cancer Res Treat 0000-00-00

...BARD1 and 0.95 % in RAD51D). Attending the intrinsic subtype, all the BRCA1/2 carriers tested had basal-like subtype. Am...

Identification of germline alterations in breast cancer predisposition genes ...

Ng(P S),Wen(W X),Fadlullah(M Z H),Yoon(S Y... Clin Genet 0000-00-00

...BARD1. Our study shows that BRCA1 and BRCA2 account for the majority of genetic predisposition to breast cancer in our c...

NRAGE is involved in homologous recombination repair to resist the DNA-damagi...

Yang(Q),Pan(Q),Li(C),Xu(Y),Wen(C),Sun(F) Cell Death Differ 0000-00-00

...BARD1, in a ubiquitin-proteolytic pathway, but also chaperons the interaction between BARD1 and RNF8 via their RING doma...

Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to...

Densham(Ruth M),Garvin(Alexander J),Stone(... Nat Struct Mol Biol 0000-00-00

...BARD1 and show that an H2A-ubiquitin fusion protein promotes DNA resection and repair in BARD1-deficient cells. BRCA1-BA...

Oxidative stress controls the choice of alternative last exons via a Brahma-B...

Fontana(Gabriele A),Rigamonti(Aurora),Lenz... Nucleic Acids Res 0000-00-00

...BARD1, which ubiquitinates the 50 kDa subunit of the 3' end processing factor CstF. This results in the inhibition of tr...

Recent advances in the research for the homolog of breast cancer associated g...

Jiao(Yue),Zhang(Yuzhou),Zhu(Yu-Xian) Sci China Life Sci 0000-00-00

BARD1 (BRCA1 associated RING domain protein 1), as an important animal tumor suppressor gene associated with many kinds ...

Defective DNA repair and chromatin organization in patients with quiescent sy...

Souliotis(Vassilis L),Vougas(Konstantinos)... Arthritis Res Ther 0000-00-00

...BARD1 and BBC3 genes implicated in apoptosis were significantly overexpressed.,Epigenetically regulated functional abnor...

Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the...

Engert(Florian),Kovac(Michal),Baumhoer(Dan... Oncotarget 0000-00-00

...BARD1 or CHEK2, were susceptible to talazoparib-induced reduction of cell viability (i.e. MG63, ZK-58,, SaOS-2 and MNNG-...

RING domain-deficient BRCA1 promotes PARP inhibitor and platinum resistance.

Wang(Yifan),Krais(John J),Bernhardy(Andrea... J Clin Invest 0000-00-00

...BARD1) interaction for stability. Functionally, Rdd-BRCA1 formed irradiation-induced foci and supported RAD51 foci forma...

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