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TP53 BRCA1 CRISPR single-cell cancer

Yi(Eun Jue),Park(Jong Ho),Lee(Hae Won),Cho(S… Ann Thorac Surg 2013-10-21

...BRCA1 gene mutations.

Semiglazova(T Iu),Klimenko(V V),Filatova(L V… Vopr Onkol 2013-09-27

...BRCA1 (breast cancer 1) are contradictory and not numerous. Analysis of the results by the end of the clinical trial wil...

Tian(Fen),Sharma(Shilpy),Zou(Jianqiu),Lin(Sh… Proc Natl Acad Sci U S A 2013-11-11

Breast cancer gene 1 (BRCA1) deficient cells not only are hypersensitive to double-strand breaks but also are hypersensi...

Ganesan(Shanthi),Bhattacharya(Poulomi),Keati… Toxicol Appl Pharmacol 2013-12-10

...Brca1 and Rad51. In contrast, Parp1 mRNA was decreased on d4 and increased on d8 of DMBA exposure, while PARP1 protein i...

Li(Mo),Lu(Lin-Yu),Yang(Chao-Yie),Wang(Shaome… Genes Dev 2013-10-24

...BRCA1 C-terminal (BRCT) domains recognizes poly(ADP-ribose) (PAR) both in vitro and in vivo. Among these FHA and BRCT do...

Tian(Chunqiao Q),Darcy(Kathleen M),Krivak(Th… Front Oncol 2013-08-21

...BRCA1/BRCA2 in epithelial ovarian cancer (EOC). This study evaluated whether common variants of BRCA1/BRCA2 are associat...

Solano(Angela Rosaria),Aceto(Gitana Maria),D… Springerplus 2013-08-20

...BRCA1 and c.5946delT in BRCA2).,We found 24 deleterious mutations (BRCA1:16; BRCA2: 8) in 38/134 (28.3%) patients, of wh...

Reinhardt(H Christian),Yaffe(Michael B) Nat Rev Mol Cell Biol 2013-11-13

...BRCA1) and FHA domains (such as in CHK2 and MDC1). Progress has been made in our understanding of the motif (or motifs) ...

Hagag(E),Shwaireb(M),Coffa(J),El Wakil(A) East Mediterr Health J 2013-08-22

...BRCA1-positive versus BRCAl-negative LGRs. Our results provide the first evidence that LGRs in BRCA1 exist in the Egypti...

Bharti(Sanjay Kumar),Sommers(Joshua A),Georg… J Biol Chem 2013-12-24

...BRCA1-associated FANCJ helicase is among those helicases able to unwind G4 DNA in vitro, and FANCJ mutations are associa...

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