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Contribution of the PALB2 c.2323C>T [p.Q775X] founder mutation in well-defined …

Tischkowitz(Marc),Sabbaghian(Nelly),Hamel(Na… BMC Med Genet 2013-03-14

...BRCA1 and BRCA2 mutations reported in the French Canadian population and in 491 women of French Canadian descent who had...

Mutation screening of the BRCA1 gene in early onset and familial breast/ovarian…

Laraqui(Abdelilah),Uhrhammer(Nancy),Lahlou-A… Int J Med Sci 2013-07-12

...BRCA1 gene in 121 Moroccan women diagnosed with breast cancer. All cases completed epidemiology and family history quest...

Molecular cytogenetics as a clinical test for prognostic and predictive biomark…

Gunn(Shelly),Reveles(Xavier),Weldon(Korrie),… J Ovarian Res 2013-03-20

...BRCA1 and/or BRCA2 gene deletions. Bi-allelic PTEN gene deletion was detected in one patient's tumor.,Clinical genomic p...

Optimal age to start preventive measures in women with BRCA1/2 mutations or hig…

Tilanus-Linthorst(Madeleine M A),Lingsma(Hes… Int J Cancer 2013-06-11

...BRCA1-, 41-57 in BRCA2- and 44-60 in high-risk families. In all, 14% of the variance in age at diagnosis, in BRCA1 even ...

Reproductive decision-making in young female carriers of a BRCA mutation.

Donnelly(L S),Watson(M),Moynihan(C),Bancroft… Hum Reprod 2013-09-26

...BRCA1 or BRCA2 gene mutation while childless.,Analysis revealed four central themes: (i) the impact of cancer on reprodu...

Is there an epigenetic component underlying the resistance of triple-negative b…

Lovato(Amanda),Panasci(Lawrence),Witcher(Mic… Front Pharmacol 2013-01-08

...Brca1/2, are prone to DNA breakages whose restoration into functional double-strand DNA is Parp dependent. This concept ...

Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mu…

Rouault(Audrey),Banneau(Guillaume),Macgrogan… PLoS One 2013-06-25

Germline BRCA1 or BRCA2 mutations account for 20-30% of familial clustering of breast cancer. The main indication for BR...

CBP and p300 histone acetyltransferases contribute to homologous recombination …

Ogiwara(Hideaki),Kohno(Takashi) PLoS One 2013-06-27

...BRCA1 and RAD51 genes, which are involved in homologous recombination (HR), a major DSB repair system. siRNA-mediated de...

BRCA1 mRNA expression as a predictive and prognostic marker in advanced esophag…

Gao(Yong),Zhu(Jing),Zhang(Xiaohui),Wu(Qingqu… PLoS One 2013-07-05

...BRCA1) expression has been found to switch the response to cisplatin- or paclitaxel-based chemotherapy. It remains uncle...

VEGF, HIF-1α expression and MVD as an angiogenic network in familial breast can…

Saponaro(Concetta),Malfettone(Andrea),Ranier… PLoS One 2013-07-05

...BRCA1 carrier cancers, but little has been reported about angiogenesis in BRCA1-2 carrier and BRCAX breast cancers. In t...

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