BRCA1/BRCA2 mutations are common and the hallmarks of high-grade serous ovarian carcinoma. We found that MIR182, a negat...
Individuals with an inherited BRCA1 or BRCA2 mutation have an elevated risk of developing breast cancer. The resulting t...
BRCA mutation-associated breast cancers are characterized by deficient homologous recombination of DNA, and 80 % of BRCA...
...BRCA1).,Using this novel gene dosage method, we have identified an APC gene deletion in a FAP patient undergoing genetic...
...BRCA1, a repressor of CYP19 transcription, was induced by pioglitazone. Consistent with these in vitro findings, treatme...
...BRCA1 was also up-regulated at the gene and protein level. The overexpression of P-glycoprotein in a resistant model dev...
...BRCA1-A complex and targets BRCA1 to DNA damage sites in response to DNA double strand breaks. Since mutations of BRCA1 ...
...BRCA1 and BRCA2 mutation carriers.,Primary human fibroblasts from three BRCA1, three BRCA2 mutation carriers, one BRCA2-...
...BRCA1 (breast cancer 1) and BRCA2 (breast cancer 2)-mutated and in sporadic ovarian cancer represents a promising field ...
...BRCA1/2 mutations and identified variables that were associated significantly with satisfaction. Prospective study of de...
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