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Comparison of low and high dose ionising radiation using topological analysis o…

Ray(Monika),Yunis(Reem),Chen(Xiucui),Rocke(D… BMC Genomics 2013-01-25

...BRCA1, ABCA1, TNFRSF1B, MLLT11 that have been associated with various types of cancers. We were also able to detect many...

BRCAness: finding the Achilles heel in ovarian cancer.

Rigakos(Georgios),Razis(Evangelia) Oncologist 2013-02-07

...BRCA1/2 are the fundamental defects in hereditary ovarian cancer that expresses a distinct phenotype of high response ra...

Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-term…

Biswas(Kajal),Das(Ranabir),Eggington(Julie M… Hum Mol Genet 2013-01-17

...BRCA1 and BRCA2 are frequently classified as variants of unknown clinical significance (VUS) due to the availability of ...

[PARP inhibitors--theoretical basis and clinical application].

Dębska(Sylwia),Kubicka(Joanna),Czyżykowski(R… Postepy Hig Med Dosw (Online) 2013-05-02

...BRCA1/2 protein which is involved in repair of DNA double-strand breaks. This phenomenon is an example of "synthetic let...

[Poly(ADP-ribose) polymerase (PARP) inhibitors in BRCA1/2 cancer therapy].

Kluzek(Katarzyna),Białkowska(Aneta),Koczorow… Postepy Hig Med Dosw (Online) 2013-05-02

...BRCA1 and BRCA2 proteins that are involved in homologous recombination, a complex repair mechanism of DNA double strand ...

BRCA1 promoter methylation status does not predict response to tamoxifen in spo…

Cerne(Jasmina Z),Zong(Lin),Jelinek(Jaroslav)… Breast Cancer Res Treat 2013-01-24

...BRCA1 promoter methylation is associated with poorer outcome in sporadic breast cancer cases treated with tamoxifen. BRC...

Expression of the BRCA1 complex member BRE predicts disease free survival in br…

Noordermeer(Sylvie M),Wennemers(Marloes),Ber… Breast Cancer Res Treat 2013-01-24

...BRCA1 DNA damage repair complex, predicted disease-free survival (DFS) in non-familial breast cancer patients. The predi...

Breast and ovarian cancer risk management in a French cohort of 158 women carry…

This(Pascale),de la Rochefordière(Anne),Savi… Fam Cancer 2013-05-03

...BRCA1 or BRCA2 germline mutation. Between 1998 and 2009, 158 unaffected women carrying a BRCA1 or BRCA2 gene mutation we...

Tubal epithelial lesions in salpingo-oophorectomy specimens of BRCA-mutation ca…

Mingels(Marjanka J J M),Roelofsen(Thijs),van… Gynecol Oncol 2013-02-06

...BRCA1/2-mutation carriers were included; ovaries and fallopian tubes, embedded completely, were reviewed. Controls inclu...

Heterochromatin instability in cancer: from the Barr body to satellites and the…

Carone(Dawn M),Lawrence(Jeanne B) Semin Cancer Biol 2013-09-30

...BRCA1, in maintaining heterochromatin will be highlighted. Many questions remain about this new area of cancer epigeneti...

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