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RING domain-deficient BRCA1 promotes PARP inhibitor and platinum resistance.

Wang(Yifan),Krais(John J),Bernhardy(Andrea... J Clin Invest 0000-00-00

...BARD1) interaction for stability. Functionally, Rdd-BRCA1 formed irradiation-induced foci and supported RAD51 foci forma...

Germline multi-gene hereditary cancer panel testing in an unselected endometr...

Ring(Kari L),Bruegl(Amanda S),Allen(Brian ... Mod Pathol 0000-00-00

...BARD1, BRCA1, BRCA2, BRIP1, NBN, PTEN, and RAD51C). Of 21 patients with deleterious mutations in Lynch syndrome genes wi...

Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial ...

Balmaña(Judith),Digiovanni(Laura),Gaddam(P... J Clin Oncol 0000-00-00

...BARD1, NBN, and BRIP1. Among all participants, 56 of 518 (11%) had a variant with conflicting interpretations ranging fr...

Oxidative stress controls the choice of alternative last exons via a Brahma-B...

Fontana(Gabriele A),Rigamonti(Aurora),Lenz... Nucleic Acids Res 0000-00-00

...BARD1, which ubiquitinates the 50 kDa subunit of the 3' end processing factor CstF. This results in the inhibition of tr...

Clinicopathological and molecular characteristics of Ku 70/80 expression in N...

Agboola(Ayodeji O J),Ebili(Henry O),Iyawe(... Pathol Res Pract 0000-00-00

...BARD1 and p27. Ku 70/80 was predictive of breast cancer-specific survival in multivariate analysis, but not of disease-f...

Outcomes of retesting BRCA negative patients using multigene panels.

Yadav(Siddhartha),Reeves(Ashley),Campian(S... Fam Cancer 0000-00-00

...BARD1 and MRE11A. Eleven out of these thirteen mutations were deemed actionable based on published guidelines. Of these ...

HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks.

Wu(Wenwen),Togashi(Yukiko),Johmura(Yoshika... Cancer Sci 0000-00-00

...BARD1). We recently found that the interaction between heterochromatin protein 1 (HP1) and BARD1 is required for the acc...

53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.

Li(Minxing),Cole(Francesca),Patel(Dharm S)... EMBO Rep 0000-00-00

...BARD1 and a defect in restart of replication forks after hydroxyurea treatment, suggesting a role of BRCA1-BARD1 in geno...

Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombinat...

Ozden(Ozkan),Bishehsari(Faraz),Bauer(Jessi... Sci Rep 0000-00-00

...BARD1 SVs with unknown function. Here we show that loss of BARD1 function through the expression of a BARD1 SV, BARD1β, ...

Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the site...

Her(Joonyoung),Soo Lee(Nam),Kim(Yonghwan),... Acta Biochim Biophys Sin (S... 0000-00-00

...BARD1, BRCA1, and MERIT40, a RAP80-associated factor. In this review, we summarize recent findings of the factors that f...

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