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'Cancer doesn't have an age': genetic testing and cancer risk management in BRC…

Werner-Lin(Allison),Hoskins(Lindsey M),Doyle… Health (London) 2013-03-08

...BRCA1/2 mutation-positive women aged 18-24 using techniques of grounded theory and interpretive description. Participant...

Pro-oxidant induced DNA damage in human lymphoblastoid cells: homeostatic mecha…

Seager(Anna L),Shah(Ume-Kulsoom),Mikhail(Jan… Toxicol Sci 2013-01-25

...BRCA1, involved in double-strand break repair, in response to low-dose pro-oxidant exposure; however, these alterations ...

Tissue-based predictors of germ-line BRCA1 mutations: implications for triaging…

de la Cruz(Jeannine),Andre(Fabrice),Harrell(… Hum Pathol 2013-01-17

...BRCA1 testing instead of initially performing mutational analysis for both BRCA1 and BRCA2.

Breast cancer genetic counseling after diagnosis but before treatment: a pilot …

Wevers(Marijke R),Hahn(Daniela E E),Verhoef(… Patient Educ Couns 2013-01-04

...BRCA1/2-mutation have an increased risk of second primary breast and ovarian tumors. Little is known about the psycholog...

Clinical significance of large rearrangements in BRCA1 and BRCA2.

Judkins(Thaddeus),Rosenthal(Eric),Arnell(Chr… Cancer 2013-01-31

Current estimates of the contribution of large rearrangement (LR) mutations in the BRCA1 (breast cancer 1, early onset) ...

BRCA genetic testing of individuals from families with low prevalence of cancer…

Shkedi-Rafid(Shiri),Gabai-Kapara(Efrat),Grin… Genet Med 2013-01-17

...BRCA1/2 may be the logical next step in populations with a high prevalence of founder mutations, such as Ashkenazi Jews....

Functional single-nucleotide polymorphisms in the BRCA1 gene and risk of saliva…

Xu(Li),Doan(Phi C),Wei(Qingyi),Li(Guojun),St… Oral Oncol 2013-05-07

Polymorphic BRCA1 is a vital tumor suppressor gene within the DNA double-strand break repair pathways, but its associati...

Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-eth…

Lee(Daphne S C),Yoon(Sook-Yee),Looi(Lai Meng… Breast Cancer Res 2013-04-24

...BRCA1, BRCA2 and TP53 by full DNA sequencing. Of the mutations identified, we examined their likely pathogenicity on the...

Haplotype analysis of two recurrent genomic rearrangements in the BRCA1 gene su…

Pertesi(M),Konstantopoulou(I),Yannoukakos(D) Clin Genet 2013-08-22

...BRCA1 gene in Greek breast cancer patients. They have been reported previously six and three times, respectively, in unr...

Insights into the targeted elimination of BRCA1-defective cancer stem cells.

Somasundaram(Veena),Srinivas(Priya) Med Res Rev 2013-05-09

...BRCA1-defective tumor progression, phenotype of BRCA1-defective cancers, role of BRCA1 in other cancers and finally at w...

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