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TP53 BRCA1 CRISPR single-cell cancer

Zilliacus(E),Meiser(B),Gleeson(M),Watts(K),T… Support Care Cancer 2013-03-27

...BRCA1/2 mutation carriers, have a high risk of ovarian cancer and metachronous breast cancer. Treatment-focused genetic ...

Almeida(Luciana O),Goto(Renata N),Pestana(Ce… FEBS J 2013-02-04

...BRCA1 and CHEK2 and upregulated TP53. Cisplatin-induced cell-cycle arrest occurred in G(0) /G(1) and S in HEK293 cells,...

Sawyer(Sarah),Mitchell(Gillian),McKinley(Joa… J Clin Oncol 2013-05-06

...BRCA1 or BRCA2 mutation compared with mutation carriers (P = 2.3 × 10(-6)). Non-BRCA1/2 women in the top quartile of the...

Pern(Franziska),Bogdanova(Natalia),Schürmann… PLoS One 2013-04-05

...BRCA1, BRCA2, PALB2, and BRD7 genes. Microfluidic array PCR and next-generation sequencing was used for BRCA1 and BRCA2 ...

Gao(Chuan),Devarajan(Karthik),Zhou(Yan),Slat… BMC Genomics 2013-05-14

...BRCA1/2, which is associated with elevated susceptibility to breast cancer. In addition to truncation mutations, multipl...

Yakovlev(Vasily A) Cancer Res 2013-03-26

...BRCA1 expression. By inhibiting BRCA1 expression, NO/RNS thereby reduces the ability of cells to repair DNA double-stran...

Jaspers(Janneke E),Kersbergen(Ariena),Boon(U… Cancer Discov 2013-06-20

...BRCA1-associated cancers. We previously reported that BRCA1-deficient mouse mammary tumors may acquire resistance to the...

da Silva(Glenda Nicioli),de Camargo(Elaine A… Mol Biol Rep 2013-04-04

...BRCA1, CCNE1, CDK2, CDK6, CDKN1A, CDKN2B, E2F4, GADD45A, MAD2L2, CCNH, SERTAD1, CDC1, and CHEK1 genes. Gemcitabine had d...

Hilbers(Florentine S),Wijnen(Juul T),Hoogerb… J Med Genet 2013-03-14

Recently, rare germline variants in XRCC2 were detected in non-BRCA1/2 familial breast cancer cases, and a significant a...

Kreipe(H H) Pathologe 2013-06-19

...BRCA1 associated cancers and to elucidate whether within the HER2 category, polysome or pseudopolysome cancer will respo...

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