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Egr-1 regulates the transcription of the BRCA1 gene by etoposide.

Shin(Soon Young),Kim(Chang Gun),Lee(Young Ha… BMB Rep 2013-08-19

...BRCA1 gene. However, only a few studies have reported on the mechanism underlying the regulation of BRCA1 expression in ...

High LET radiation amplifies centrosome overduplication through a pathway of γ-…

Shimada(Mikio),Hirayama(Ryoichi),Komatsu(Ken… Int J Radiat Oncol Biol Phys 2013-06-26

...Brca1-deficient cells. Because NBS1/BRCA1 is implicated in monoubiquitination of γ-tubulin, we subsequently tested wheth...

Proposed roadmap to stepwise integration of genetics in family medicine and cli…

Houwink(Elisa Jf),Sollie(Annet W),Numans(Mat… Clin Transl Med 2013-03-19

...BRCA1 mutation as an example.

BRCA1 is a novel target to improve endothelial dysfunction and retard atheroscl…

Singh(Krishna K),Shukla(Praphulla C),Quan(Ad… J Thorac Cardiovasc Surg 2013-11-08

...BRCA1 is basally expressed in endothelial cells. BRCA1 overexpression protected and BRCA1 silencing exaggerated inflamma...

BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionall…

Stordal(Britta),Timms(Kirsten),Farrelly(Ange… Mol Oncol 2013-12-23

...BRCA1/2 genes were sequenced in 41 ovarian cell lines, mRNA expression of BRCA1/2 and gene methylation status of BRCA1 w...

Excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive …

Adank(Muriel A),Verhoef(Senno),Oldenburg(Rog… Eur J Cancer 2013-07-05

...BRCA1/2 breast cancer setting.,Cancer incidences were compared between first degree relatives of 107 familial breast can...

NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruit…

Ray(Alo),Milum(Keisha),Battu(Aruna),Wani(Gul… DNA Repair (Amst) 2013-08-21

...BRCA1 was significantly reduced or abrogated in mutant cells. Furthermore, UV exposure of cells defective in DDB2 or XPC...

A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer.

Satija(Yatendra Kumar),Bhardwaj(Abhishek),Da… Int J Cancer 2013-12-09

...BRCA1 and VHL RING type ligases function as tumor suppressors and play an important role in DNA repair and hypoxia respo...

Histone lysine trimethylation or acetylation can be modulated by phytoestrogen,…

Dagdemir(Aslihan),Durif(Julie),Ngollo(Marjol… Epigenomics 2013-09-04

...BRCA1, ERα, ERβ, SRC3 and P300) for analysis.,Soy phytoestrogens induced a decrease in trimethylated marks and an increa...

Poly(adenosine diphosphate-ribose) polymerase expression in BRCA-proficient ova…

Gan(Alex),Green(Andrew R),Nolan(Christopher … Hum Pathol 2013-09-16

...BRCA1 profile (P = .04). Analysis of the combined expression of PARP1 and BRCA1 revealed that high expression of PARP1 i...

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