...BRCA1 tumor-suppressor gene regulate aromatase expression. In this issue of the journal (beginning on p. 1183), Subbaram...
...BRCA1; 53BP1 loss rescues homologous recombination (HR) in BRCA1-deficient cells.,RNF168 depletion suppresses HR defects...
...BRCA1-associated protein-1 familial melanoma syndrome, recently described somatic mutations, and chromosomal copy number...
Defects in BRCA1, BRCA2, and other members of the homologous recombination pathway have potential therapeutic relevance ...
...BRCA1 expression in human hTERT-immortalized fibroblasts (shBRCA1) using an shRNA lentiviral approach. As expected, shBR...
...BRCA1-null ovarian cancer cells on adjacent tumor-associated stromal fibroblasts. Our results directly show that BRCA1-n...
...BRCA1 and BRCA2 is the participation in dsDNAbreak repair via homologous recombination. BRCA1 and BRCA2 mutations, which...
BRCA1 functions as a tumor suppressor gene and germline and somatic mutations in this gene have been shown to be associa...
...BRCA1 or BRCA2 (BRCA1/2) mutations face difficult decisions about managing their high risks of breast and ovarian cancer...
...BRCA1 in vitro. Furthermore, the N terminus of BRCA1 mediates the interaction between BRCA1 and FBXO44. Overexpression o...
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