Detection of mutations in hereditary breast and ovarian cancer-related BRCA1 and BRCA2 genes is an effective method of c...
...BRCA1 or BRCA2 mutation carrier or family history including at least one first- or second-degree relative with ovarian o...
...BRCA1/2 mutations were found in two out of twenty OC patients (10 %). Eleven patients (29 %) received surveillance recom...
...BRCA1 mutations have TNBC, the prevalence of BRCA1 mutations in patients with TNBC remains unclear. Deciphering the rela...
...BRCA1 is one of the common hereditary cancer predisposition genes and encodes for an ubiquitin ligase. Ubiquitin ligases...
...BRCA1, BRCA2, PALB2, ATM, CDKN2A, APC, MLH1, MSH2, MSH6, PMS2, PRSS1, and STK11. Recognition of members of high-risk fam...
...BRCA1 and RAD51L1.,Our analyses have provided several loci of interest to pursue in these high-risk pedigrees and illust...
...BRCA1 and γ-H2A.X. The sequential appearance of WICH and BRCA1/γ-H2A.X implicate each as performing important but distin...
...Brca1 pathways are each associated with triple-negative and Basal-like subtypes. Our mouse genetic studies demonstrate t...
...BRCA1 tumor suppressor gene are commonly found in hereditary breast cancer. Similarly, downregulation of BRCA1 protein e...
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