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TP53 BRCA1 CRISPR single-cell cancer

Penkert(Judith),Schlegelberger(Brigitte),Ste… Fam Cancer 2013-04-23

...BRCA1 (breast cancer 1, early onset) pathways. As low BRD7 expression levels have been linked to p53-wild-type breast tu...

Gaj(Pawel),Kluska(Anna),Nowakowska(Dorota),B… Fam Cancer 2013-04-23

Possession of a BRCA1/2 mutation increases risk of contralateral breast and ovarian cancer recurrence and may have an im...

Hoskins(Lindsey M),Werner-Lin(Allison) J Genet Couns 2013-07-03

Much of the extant literature addressing the psychosocial aspects of BRCA1/2 mutation testing and risk management aggreg...

Ozcelik(Hilmi),Shi(Xuejiang),Chang(Martin C)… J Mol Diagn 2013-01-03

...BRCA1 and BRCA2 (BRCA1/2) have a markedly elevated risk of developing breast and ovarian cancers. The first-generation o...

Ng(T),Irshad(S),Stebbing(J) Oncogene 2013-07-29

The multifunctional roles of BRCA1 include its ability to regulate transcriptional processes that control differentiatio...

Esteban Cardeñosa(Eva),de Juan Jiménez(Inmac… Fam Cancer 2013-04-23

...BRCA1/2 mutations and 210 non-carriers) and 198 sporadic BC/OC. The polymorphisms were assessed by real-time PCR using p...

Reitsma(Welmoed),de Bock(Geertruida H),Ooste… Eur J Cancer 2013-02-27

...BRCA1-carriers, 115 BRCA2-carriers and 57 BRCA-negative women at a median age of 44.0 years. Four occult invasive cancer...

Chan(Maurice),Ji(Shen Mo),Yeo(Zhen Xuan),Gan… J Mol Diagn 2013-02-28

...BRCA1 and BRCA2 genes, generated using a PCR-based, multiplexed NGS approach using the SOLiD 4 (n = 24) and Ion Torrent ...

Hoskins(Lindsey M),Greene(Mark H) Qual Health Res 2013-12-03

...BRCA1/2 mutations face difficult decisions in managing their hereditary breast/ovarian cancer risk. Through this Nationa...

Novaković(Srdjan),Milatović(Maša),Cerkovnik(… Int J Oncol 2013-03-22

...BRCA1 and BRCA2 genes. Three novel mutations were detected: one in BRCA1 - c.1193C>A (p.Ser398*) and two in ...

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