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TP53 BRCA1 CRISPR single-cell cancer

Mikeska(Thomas),Alsop(Kathryn),,Mitchell(Gil… J Ovarian Res 2013-04-29

...BRCA1 and BRCA2 genes and occur predominantly in high-grade serous cancer. Another member of the BRCA/FA pathway, PALB2 ...

Yang(Xuejiao),Zhang(Zhan),Wang(Xichen),Wang(… Toxicol Appl Pharmacol 2013-10-18

...BRCA1, and H2AX, rather than the proteins related to DNA repair. These effects could be almost completely inhibited by 1...

Becherel(Olivier J),Yeo(Abrey J),Stellati(Al… PLoS Genet 2013-06-25

...Brca1-dependent manner, and in its absence there was incomplete localisation of DNA damage response proteins to the XY c...

Ou(Jianghua),Wu(Tao),Sijmons(Rolf),Ni(Duo),X… J Breast Cancer 2013-05-08

...BRCA1; 1627A-T [K467X], 6873delCTCC and 9481delA in BRCA2) in this cohort. The prevalence of BRCA1/2 germline mutation w...

D'Andrea(Alan D) Cancer Discov 2013-09-24

...BRCA1 alleles. These findings further implicate BRCA1 in the Fanconi anemia/BRCA pathway and have important implications...

Anantha(Rachel W),Alcivar(Allen L),Ma(Jiangl… PLoS One 2013-10-22

...BRCA1, BRCA2 and PALB2 form a complex and play key roles in homologous recombination (HR), DNA double strand break (DSB)...

Apostolou(Paraskevi),Fostira(Florentia) Biomed Res Int 2013-11-11

...BRCA1 and BRCA2 genes. As sequencing technologies evolve, more susceptible genes have been discovered and BRCA1 and BRCA...

Jiang(Wenjie),Wu(Yili),Jiang(Xiubo) Gynecol Oncol 2013-06-28

...BRCA1 mutation carriers (RR=0.69, P<0.01). A linear dose-response relationship was found for breast cancer risk with cof...

Probst-Hensch(Nicole M),Brand(Angela) Ther Umsch 2013-07-09

...BRCA1 and BRCA2 mutations dramatically. In recent years, the research has moved towards the decoding of the genetic caus...

Moiseyenko(Vladimir M),Volkov(Nikita M),Susp… Med Oncol 2013-10-24

...BRCA1 allele, thus confirming the causative role of BRCA1 heterozygosity in GC predisposition. RNA expression of TS, DPD...

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