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TP53 BRCA1 CRISPR single-cell cancer

Stevens(Kristen N),Vachon(Celine M),Couch(Fe… Cancer Res 2013-06-25

...BRCA1 and BRCA2 breast cancer susceptibility genes have been associated with up to 15% of TNBC, and TNBC accounts for 70...

Ingham(Sarah Louise),Warwick(Jane),Buchan(Ia… J Med Genet 2013-12-09

...BRCA1/2 genes confer ovarian, alongside breast, cancer risk. We examined the risk of developing ovarian cancer in BRCA1/...

Madjd(Zahra),Karimi(Adel),Molanae(Saadat),As… Cell J 2013-03-20

...BRCA1 mutation carriers suggest that BRCA1 may function as a stem-cell regulator.,In the present experimental study we e...

Kass(Elizabeth M),Helgadottir(Hildur R),Chen… Proc Natl Acad Sci U S A 2013-06-11

...Brca1, a significant reduction in HDR was detected, showing that BRCA1 is critical for HDR in somatic cell types. Consis...

Ternovoĭ(S K),Matkhev(S),Meladze(N V),Solopo… Vestn Rentgenol Radiol 2013-05-14

...BRCA1/2 gene mutations was determined in patients with BC identified during the mammographic screening. A relationship w...

Guinan(Emer M),Hussey(Juliette),McGarrigle(S… BMC Cancer 2013-09-16

...BRCA1 or BRCA2, the risk of developing breast or ovarian cancer is significantly increased. In recent years there has be...

Masojć(Bartłomiej),Górski(Bohdan),van de Wet… Hum Mutat 2013-09-06

...BRCA1, a singular polymorphism in CCND1 and somatic mutations in KRAS and BRAF genes. The validation set consisted of 14...

Sudo(Hideki),Yamada(Katsuhisa),Iwasaki(Koji)… PLoS One 2013-09-10

...Brca1, Cdc25, Gadd45, Hus1, Ppm1D, Rad 9, Tp53, and Cyclin D1. Both p27(Kip1) and p53 protein expression was upregulated...

Syed(B M),Green(A R),Paish(E C),Soria(D),Gar… Br J Cancer 2013-05-21

...BRCA1 and 2, E-cadherin, luminal cytokeratins, HER3, HER4, MDM2 and 4 and low expression of human epidermal growth facto...

Lesnock(J L),Darcy(K M),Tian(C),Deloia(J A),… Br J Cancer 2013-05-28

...BRCA1) is a tumour-suppressor gene associated with familial epithelial ovarian cancer (EOC). Reduced BRCA1 expression is...

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