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TP53 BRCA1 CRISPR single-cell cancer

Larsen(Martin J),Kruse(Torben A),Tan(Qihua),… PLoS One 2013-12-30

...BRCA1/2 mutation status. We found that breast tumors from BRCA1 and BRCA2 mutation carriers display characteristic RNA e...

Zhang(Qing-li),Zhang(Qing-hui),Cong(Hua),Zha… Zhonghua Bing Li Xue Za Zhi 2013-09-16

...BRCA1 gene was not detected in any of 10 cases studied.,BRCA1 cytoplasmic expression statistically correlates with the d...

Reczek(Colleen R),Szabolcs(Matthias),Stark(J… J Cell Biol 2013-08-01

...BRCA1 tumor suppressor, which interacts with CtIP in a phospho-dependent manner, has also been implicated in DSB repair ...

Demsky(R),McCuaig(J),Maganti(M),Murphy(K J),… Gynecol Oncol 2013-09-13

...BRCA1 and BRCA2 genes. This study aimed to determine the proportion of these women who are seen for genetic counseling a...

Lin(William Y),Wilson(John H),Lin(Yunfu) DNA Repair (Amst) 2013-10-21

...BRCA1 showed similar effects as the knockdowns of NHEJ factors. In contrast, knockdown of components involved in alterna...

Bernstein(Jonine L),Thomas(Duncan C),Shore(R… Eur J Cancer 2013-11-13

...BRCA1 or BRCA2 (BRCA1/BRCA2) mutations are at very high risk of developing breast cancer, including asynchronous contral...

Tram(Eric),Savas(Sevtap),Ozcelik(Hilmi) PLoS One 2013-12-30

...BRCA1 and 13.95% (6/43) BRCA2 VUS altered the phosphorylation of BRCA1 and BRCA2. We highlight six BRCA1 (K309T, S632N, ...

Dressler(Anne Catharina),Hudelist(Gernot),Fi… J Cancer Res Clin Oncol 2013-09-17

...BRCA1 mutant breast cancer cells, which lack the ability to repair DNA damages by homologous recombination, p27 is down-...

Cybulski(C),Wokołorczyk(D),Kluźniak(W),Kashy… Br J Cancer 2013-09-10

...BRCA1 (5382insC, 4153delA and C61G), for four alleles in CHEK2 (1100delC, IVS2+1G>A, del5395 and I157T), for one allele ...

Krenciute(Giedre),Liu(Shangfeng),Yucer(Nur),… J Biol Chem 2013-09-27

...BRCA1 to sites of DNA damage. Together our results suggest that the nuclear BAG6 complex is an effector in DNA damage re...

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