...Spo11 homolog) to eliminate meiotic DNA double-strand breaks (DSBs) suppressed the segregation defect in dbl2Δ cells, in...
...Spo11. Repair of these DSBs is highly regulated to create crossovers between homologs that are distributed throughout th...
Meiotic recombination initiates following the formation of DNA double strand breaks (DSBs) by the Spo11 endonuclease ear...
...Spo11-oligonucleotide complexes and altered Spo11-oligonucleotide lengths, consistent with conserved roles for Tel1 in c...
...spo11 cells, but not in a coupling-defective mutant (spo11 zip1 haploid and diploid yeast). This pattern is also observe...
DNA double-strand breaks (DSBs) are induced by SPO11 during meiosis to initiate recombination-mediated pairing and synap...
...SPO11, chromatin, and the histone methyltransferase PRDM9. At large scale, DSB formation is suppressed on non-homologous...
...Spo11)-oligonucleotides from 5' DNA ends followed by resection to generate invasive 3' single-stranded DNA tails. The Mr...
...Spo11-catalyzed double strand break formation; their contribution to crossover recombination remains undefined. Using th...
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