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Expression of histone H2AX phosphorylation and its potential to modulate adriam…

Zhou(Fen),Mei(Heng),Wu(Qiuling),Jin(Runming) J Huazhong Univ Sci Technolog… 2013-04-08

...BRCA1. These results illustrate chemosensitivity can partly be measured by detecting γH2AX and drug resistance can be re...

Eradication of breast cancer cells in patients with distant metastasis: the fin…

Ito(Yoshinori),Iwase(Takuji),Hatake(Kiyohiko) Breast Cancer 2013-02-01

...BRCA1-disabled breast cancer. Cancer stem cells could be the major obstacle to achieving a cure in systemic treatment. E...

The impact of prophylactic salpingo-oophorectomy on quality of life and psychol…

Finch(Amy),Metcalfe(Kelly A),Chiang(Jaclyn),… Psychooncology 2013-05-22

...BRCA1 or BRCA2 mutation were invited to participate. Participants completed three questionnaires (SF-12(®) Health Survey...

BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica.

Gutiérrez Espeleta(G A),Llacuachaqui(M),Garc… Clin Genet 2013-03-21

...BRCA1 mutation was found (C3522T). The family with the BRCA1 mutation had five cases of gastric cancer. Families with BR...

PARP inhibitors: its role in treatment of cancer.

Chen(Alice) Chin J Cancer 2013-03-20

...BRCA1- or BRCA2-associated ovarian or breast cancers, and in combination with chemotherapy in triple negative breast can...

BRCA1/2 testing: uptake, phenocopies, and strategies to improve detection rates…

Fischer(C),Engel(C),Sutter(C),Zachariae(S),S… Clin Genet 2013-03-21

...BRCA1/2-negative index patient and in eight families a BRCA1/2 mutation was found. In BRCA1/2 mutation-positive families...

An ELISA-based high throughput protein truncation test for inherited breast can…

Lim(Mark J),Foster(Gabriel J),Gite(Sadanand)… Breast Cancer Res 2013-02-12

...BRCA1/2 analysis.,Segments of exons 11 of BRCA1/2 open reading frames were PCR amplified from either blood derived genom...

Advantage of high-resolution melting curve analysis over conformation-sensitive…

de Juan Jiménez(Inmaculada),Cardeñosa(Eva Es… Clin Chim Acta 2013-08-07

...BRCA1 and BRCA2 (BRCAs) genes is a time-consuming and costly procedure that demands faster and cheaper alternative metho...

Age-specific incidence rates for breast cancer in carriers of BRCA1 mutations f…

Møller(P),Maehle(L),Vabø(A),Clark(N),Sun(P),… Clin Genet 2013-07-12

Incidence rates of breast cancer among women with a BRCA1 mutation vary according to their reproductive histories and co...

BRCA1 gene therapy reduces systemic inflammatory response and multiple organ fa…

Teoh(H),Quan(A),Creighton(A K),Annie Bang(K … Gene Ther 2013-06-11

...BRCA1 adenovirus (AdBRCA1) or the adeno-CMV-null vector (Adnull). The 24-h post-CLP mortality was 2.8% vs 17.9% (P<0.001...

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