...BRCA1 ER-positive breast cancers constitute sporadic cancers arising in the context of a BRCA1 germline mutation rather ...
...BRCA1, ATR, and γH2AX on unsynapsed chromosomes, followed by local changes on the sex chromatin, including histone modif...
...BRCA1. We identified a total of 3,545 proteins, of which 801 were significantly differentially regulated between the BRC...
...BRCA1 and BRCA2 as FPC candidate genes. Results The CDKN2A mutation rate in the 225 PC cases was 5.7%. The CDKN2A found...
...BRCA1/2 genes were identified in 65 (8.6%) patients among total 758 patients [BRCA1 mutation: 25 (3.3%), BRCA2 mutation:...
...Brca1-deficient cells with an IC(50) value of 49.0 μM and displayed >10-fold selectivity over wild type counterparts. Bi...
...BRCA1-associated breast cancer (p<0.001) and invasive breast cancer overexpressing EGFR (p = 0.019). We observed a corre...
...BRCA1 status. The use of antimetabolite drugs and the level of expression of their cellular targets seem to be correlate...
...BRCA1 or BRCA2 mutations exhibited a characteristic combination of substitution mutation signatures and a distinctive pr...
...BRCA1/2 genes (33 BRCA1 and 47 BRCA2), 31 were new UVs (10 BRCA1 and 21 BRCA2), 7 were rare UVs (4 BRCA1 and 3 BRCA2) an...
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