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Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic se…

Szabova(Ludmila),Yin(Chaoying),Bupp(Sujata),… Cancer Res 2012-12-04

...BRCA1/2. Using Cre-conditional alleles and intrabursal induction by Cre-expressing adenovirus in genetically engineered ...

[Triple negative breast cancer--prognostically highly unfavourable group cancer…

Minár(L),Hvizdová(M),Weinberger(V),Jandáková… Ceska Gynekol 2012-07-05

...BRCA1 mutations. Elementary systemic treatment is chemotherapy. Together continues the effort of highly targeted therapy...

Identification of the prevalent BRCA1 and BRCA2 mutations in the female populat…

Dutil(Julie),Colon-Colon(Jose L),Matta(Jaime… Cancer Genet 2012-08-28

...BRCA1 and five mutations in BRCA2. Three recurrent mutations (BRCA1 del exon1-2, BRCA2 4150G>T, and BRCA2 6027del4) acco...

KRas-LCS6 polymorphism does not impact on outcomes in ovarian cancer.

Caiola(Elisa),Rulli(Eliana),Fruscio(Robert),… Am J Cancer Res 2012-10-02

...BRCA1/BRCA2, HER2, KRAS and PI3K genes have been associated to this pathology. A genomic variant in the 3' untraslated r...

The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like …

Jönsson(Göran),Staaf(Johan),Vallon-Christers… Cancer Res 2012-12-04

...BRCA1/2 mutation carriers. Focusing on the RB1 locus, we analyzed 33 BRCA1-mutated, 36 BRCA2-mutated, and 48 non-BRCA1/2...

The application of nonsense-mediated mRNA decay inhibition to the identificatio…

Johnson(Julie K),Waddell(Nic),,Chenevix-Tren… BMC Cancer 2012-12-21

...BRCA1/2 breast cancer families in order to identify additional high-risk breast cancer susceptibility genes.,We applied ...

[Triple-negative breast cancer: analysis of patients diagnosed and/or treated a…

Svoboda(M),Navrátil(J),Fabian(P),Palácová(M)… Klin Onkol 2012-08-07

...BRCA1 gene was documented. The aim of our study was to create a representative group of patients with TNBC, which could ...

BRCA mutation frequency and patterns of treatment response in BRCA mutation-pos…

Alsop(Kathryn),Fereday(Sian),Meldrum(Cliff),… J Clin Oncol 2012-09-24

The frequency of BRCA1 and BRCA2 germ-line mutations in women with ovarian cancer is unclear; reports vary from 3% to 27...

Evaluation of association methods for analysing modifiers of disease risk in ca…

Barnes(Daniel R),Lee(Andrew),,,Easton(Dougla… Genet Epidemiol 2012-10-19

There is considerable evidence indicating that disease risk in carriers of high-risk mutations (e.g. BRCA1 and BRCA2) va...

Prevalance of BRCA1 and BRCA2 mutations in familial breast cancer patients in L…

Jalkh(Nadine),Nassar-Slaba(Jinane),Chouery(E… Hered Cancer Clin Pract 2012-10-02

...BRCA1 and BRCA2 account for less of the half of these inherited cases. In Lebanon, breast cancer represents the principa...

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