...BRCA1 and BRCA2 genes are strong predictors of breast and/or ovarian cancer development. However currently known suscept...
...BRCA1/2 mutation carriers understand genetic inheritance and consider a child's inheritance of a BRCA1/2 mutation, given...
...BRCA1 gene mutation-dependant. Some authors claim that clinical features, the course of the disease and prognosis of BRC...
...BRCA1 or BRCA2 mutations) or Lynch syndrome had been documented, but no action was recorded, and its significance was no...
...BRCA1 compared with BRCA2 carriers.,A consecutive series of adnexal cancers in BRCA1/2 mutation carriers diagnosed in 19...
...BRCA1. Gamma-H2AX labels exclusively the differential (asynaptic) region of the X chromosome. A single focus is labeled ...
...BRCA1 carriers, and 52% (95% CI, 46%-58%) for BRCA2 carriers. After adjusting for study and year of diagnosis, BRCA1 and...
...BRCA1 or BRCA2 germ-line mutations have an average risk of 39% and 11% respectively of developing ovarian cancer by the ...
...BRCA1 with 20% of cases giving a family history. Risk factors for MBC are poorly understood and include working in high-...
...BRCA1 or p53 [6]. There is no current evidence that mutations in PTEN account for a substantial proportion of familial b...
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