...BRCA1, FANCD, FANCF, PARP1, E-cadherin, and Rb1 were all activated in the in situ and down-regulated in the invasive car...
...BRCA1 gene mutations have been associated with breast cancer, BRCA1 mutations have been also involved in other functions...
...BRCA1 and BRCA2, the genetic causes of the majority of early-onset cases are unexplained. Since germ line mutations in t...
...BRCA1 and BARD1.,These results show that intracellular levels of Spt6 are fine-tuned by PAAF1 and proteasome, which is r...
...BRCA1/2 combined mutation prediction to BOADICEA, but performed better than BOADICEA in BRCA1 mutation prediction (AUC 9...
...BRCA1) and BRCA2 genes have a significant risk of developing breast and ovarian cancer over the course of their lifetime...
...BRCA1 or RRM1, could predict response to platinum, taxanes and gemcitabine-based therapies, respectively, and might impr...
...BRCA1 and BRCA2 been clearly defined. However, it is clear that defects in HR and other DNA repair pathways are importan...
...BRCA1 carriers, and 52% (95% CI, 46%-58%) for BRCA2 carriers. After adjusting for study and year of diagnosis, BRCA1 and...
In the past, hereditary ovarian carcinoma was attributed almost entirely to mutations in BRCA1 and BRCA2, with a much sm...
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