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Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vi…

Dong(Yizhou),Nakagawa-Goto(Kyoko),Lai(Chin-Y… J Nat Prod 2012-05-22

...Brca1/p53 mutations. The new derivatives 10, 16 (ABO), 22, and 27 (ATBO) were the most active analogues, with IC(50) val...

BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and p…

Dever(Seth M),White(E Railey),Hartman(Matthe… Cell Cycle 2012-09-14

...BRCA1) in the DNA damage response may be of the most critical importance to understanding these processes. The BRCA1 pro...

MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.

Liu(Zhaojian),Liu(Jinsong),Segura(Miguel F),… J Pathol 2012-11-27

...BRCA1) and metastasis suppressor 1 (MTSS1) expression as well as its positive regulation of the oncogene high-mobility g...

Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelio…

Yoshikawa(Yoshie),Sato(Ayuko),Tsujimura(Tohr… Cancer Sci 2012-06-18

...BRCA1-associated protein 1 (BAP1) in 23 malignant mesotheliomas (MMs), 16 epithelioid and seven non-epithelioid, consist...

Accuracy of BRCA1/2 mutation prediction models for different ethnicities and ge…

Kwong(Ava),Wong(Connie H N),Suen(Dacita T K)… World J Surg 2012-08-23

...BRCA1/2 combined mutation prediction to BOADICEA, but performed better than BOADICEA in BRCA1 mutation prediction (AUC 9...

Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor…

Long(M),Yin(G),Liu(L),Lin(F),Wang(X),Ren(J),… Cancer Gene Ther 2012-07-20

...BRCA1 protein expression. Furthermore, there were no obvious phenotypes changes observed in normally differentiated epit...

Epigenetic modification and cancer: mark or stamp?

Foulkes(William D) Endocr Relat Cancer 2012-10-17

...BRCA1 and BRCA2 germline mutation carriers' by Bijron et al. published in the February 2012 issue of Endocrine-Related C...

An integer linear programming approach for finding deregulated subgraphs in reg…

Backes(Christina),Rurainski(Alexander),Klau(… Nucleic Acids Res 2012-05-29

...BRCA1 mutation carriers and of epithelial cells without BRCA1 mutation. Our results suggest that oxidative stress plays ...

The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutatio…

Laitman(Yael),Kuchenbaecker(Karoline B),Rant… Breast Cancer Res Treat 2012-08-22

...BRCA1 mutation carriers. The effect of this variant on breast and ovarian cancer risks in non-Jewish BRCA1/BRCA2 mutatio...

Preferential binding of IFI16 protein to cruciform structure and superhelical D…

Brázda(Václav),Coufal(Jan),Liao(Jack C C),Ar… Biochem Biophys Res Commun 2012-09-06

...BRCA1 and p53. It is also reported that IFI16 protein is capable of binding p53 and cMYC gene promoters. Here, we demons...

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