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The threshold level of adenomatous polyposis coli protein for mouse intestinal …

Li(Q),Ishikawa(TO),Oshima(M),Taketo(MM) Cancer Res 2005-10-01

...Apc(Delta716) mice, heterozygotes of an Apc null allele. Like in Apc(Delta716) mice, loss of the wild-type Apc allele wa...

Molecular characterization of parathyroid tumors from two patients with heredit…

Andreasson(A),Sulaiman(L),do Vale(S),Martins… Fam Cancer 2012-09-00

...APC gene. We sequenced the entire APC gene in tumor and constitutional DNA from both cases, assessed the levels of APC p...

APC in the nervous system.

Senda(T),Yamada(NO),Onouchi(T) Med Mol Morphol 2026-09-00

...Apc gene/Apc protein is deeply involved in brain development and morphogenesis. In the postnatal brain, Apc/Apc is invol...

Mitotic regulation of the APC activator proteins CDC20 and CDH1.

Kramer(ER),Scheuringer(N),Podtelejnikov(AV),… Mol Biol Cell 2000-05-00

...APC(CDC20) and APC(CDH1); the phosphorylation of APC subunits is required to allow APC activation by CDC20, whereas the ...

Novel self-association of the APC molecule affects APC clusters and cell migrat…

Li(Z),Kroboth(K),Newton(IP),Näthke(IS) J Cell Sci 2008-06-01

...APC) gene are responsible for familial and sporadic colorectal cancer. APC is a multifunctional protein involved in cell...

[Comparison of adhesive seal morphology between APC™ PLUS and APC™ Flash-Free A…

Jung(A),Egloff(B),Schweitzer(T),Aranda(L),Ra… Orthod Fr 2018-00-00

...APC™ PLUS adhesive-coated brackets and APC™ Flash-Free brackets. In vitro bonding of esthetic brackets in the CLARITY™ A...

Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP.

Dikovskaya(D),Li(Z),Newton(IP),Davidson(I),H… J Cell Sci 2010-03-01

...Apc function. We identified importin-beta as a binding partner of Apc that regulates its effect on MTs. Apc binds import...

Molecular analysis of APC promoter methylation and protein expression in colore…

Chen(J),Röcken(C),Lofton-Day(C),Schulz(HU),M… Carcinogenesis 2005-01-00

...APC protein levels were independent of the presence of APC promoter methylation or gene mutations. In summary, APC promo...

Species-dependent neuroprotection by activated protein C mutants with reduced a…

Guo(H),Wang(Y),Singh(I),Liu(D),Fernández(JA)… J Neurochem 2009-04-00

...APC is neuroprotective in rodent models of stroke. But, an APC variant with reduced anticoagulant activity, 3K3A-APC, co...

Inactivation of germline mutant APC alleles by attenuated somatic mutations: a …

Su(LK),Barnes(CJ),Yao(W),Qi(Y),Lynch(PM),Ste… Am J Hum Genet 2000-09-00

...APC, as did the wild-type APC. Mutation analysis showed that both APC(AS9) and the wild-type APC alleles were somaticall...

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