Cai(R),Khan(S),Chen(X),Li(H),Tan(J),Tian(Y),… Toxicol Appl Pharmacol 2024-00-00

...APPL2 and regulating the CDK2-Rb-E2F1 signaling pathway. In summary, ach-miR-276a-3p, derived from A. chinensis, has ant...

Engin(A) Adv Exp Med Biol 2017-00-00

...APPL2 may alter adiponectin efficiency and activity. However, APPL2 blocks adiponectin signaling through AdipoR1 and Adi...

Ma(XW),Ding(S),Ma(XD),Gu(N),Guo(XH) Chin Med J (Engl) 2011-11-00

...APPL2 as an adaptor for adiponectin receptors mediates the signaling pathway of adiponectin which acts as an anti-athero...

Tan(Y),You(H),Wu(C),Altomare(DA),Testa(JR) J Biol Chem 2010-02-26

...Appl2, we used small interfering RNA to knock down Appl2 expression in Appl1(-/-) MEFs. Unexpectedly, cell survival was ...

Rashid(S),Parveen(Z),Ferdous(S),Bibi(N) Comput Biol Chem 2013-12-00

...APPL2 dimerization. There is an evidence that both PH and BAR domains of APPL proteins exhibit alternately conserved reg...

Liu(Z),Xiao(T),Peng(X),Li(G),Hu(F) Cell Signal 2017-00-00

...APPL2, in mediating adiponectin, insulin, endosomal trafficking and other signaling pathways. A deep understanding of AP...

Pereira(M),Ko(JH),Logan(J),Protheroe(H),Kim(… Elife 2020-00-19

...Appl2-/-, Deptor-/-) and myeloid-specific Slc40a1 knockout mice displayed abnormal bone phenotypes. We report opposing e...

Song(J),Mu(Y),Li(C),Bergh(A),Miaczynska(M),H… Oncotarget 2016-01-05

...APPL2 are required for TGFβ-induced nuclear translocation of TβRI-ICD and for cancer cell invasiveness of human prostate...

Engin(A) Adv Exp Med Biol 2024-00-00

...APPL2 may alter APN efficiency and activity. However, APPL2 blocks adiponectin signaling through AdipoR1 and AdipoR2 bec...

Mehravar(M),Jafarzadeh(M),Kay(M),Najafi(H),H… Gene 2017-03-01

...APPL2, OCC-1 and NUAK1 flanking genes are located in 12q23.3 locus which is known as a potential cancer predisposition l...