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Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipo...

Park(Ui-Hyun),Yoon(Seung Kew),Park(Taesun)... J Biol Chem 2011-03-02

...ASXL2 expression. Knockdown of ASXL1 and ASXL2 had reciprocal effects on adipogenesis. In chromatin immunoprecipitation ...

Functional conservation of Asxl2, a murine homolog for the Drosophila enhance...

Baskind(Heather A),Na(Lucy),Ma(Quanhong),P... PLoS One 2009-05-14

...Asxl2 mutant mouse from a gene-trap ES cell line.,We show that the Asxl2 gene trap is expressed at high levels in specif...

Alteration of enhancer of polycomb 1 at 10p11.2 is one of the genetic events ...

Nakahata(Shingo),Saito(Yusuke),Hamasaki(Ma... Genes Chromosomes Cancer 2009-10-02

...ASXL2) gene at 2p23.3 (EPC1/ASXL2). In the case with an acute-type ATLL, who carried a der(10)del(10)(p11.2)del(10)(q22q...

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and ...

Gelsi-Boyer(Véronique),Trouplin(Virginie),... Br J Haematol 2009-09-10

...ASXL2, UTX, CXXC4, CXXC5, TET2, TET3). To validate some of these candidates we studied the sequence of ASXL1. We found m...

Agenesis of the corpus callosum, optic coloboma, intractable seizures, cranio...

Li(Jiang),Shivakumar(Shilpa),Wakahiro(Mari... Am J Med Genet A 2007-11-09

...ASXL2, and ZNF462, which have previously been implicated in ACC with optic coloboma. This case presents many features si...

Characterization of Asxl1, a murine homolog of Additional sex combs, and anal...

Fisher(Cynthia L),Randazzo(Filippo),Humphr... Gene 2006-06-14

...Asxl2, and Asxl3) and identify conserved sequence features. The predicted amino acid sequence of Asxl1 has 16% identity ...

Identification and characterization of human CXXC10 gene in silico.

Katoh(Masuko),Katoh(Masaru) Int J Oncol 2005-02-09

...ASXL2, and ASXL3 are cancer-associated genes belonging to the CXXC gene family. Here, we identified and characterized CX...

Identification and characterization of ASXL2 gene in silico.

Katoh(Masuko),Katoh(Masaru) Int J Oncol 2004-05-04

...ASXL2), ASXM domain (codon 269-380 of ASXL2), and PHD domain (codon 1400-1431 of ASXL2) were conserved between human ASX...

Identification and characterization of ASXL3 gene in silico.

Katoh(Masuko),Katoh(Masaru) Int J Oncol 2004-12-28

...ASXL2. ASXL3-DTNA locus at chromosome 18q12.1 and ASXL2-DTNB locus at 2p23.3 were paralogous regions within the human ge...

ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone...

Park(U-H),Kang(M-R),Kim(E-J),Kwon(Y-S),Hur... Oncogene 0000-00-00

...ASXL2 at ERα target gene promoters. ASXL2 forms a complex with histone methylation modifiers including LSD1, UTX and MLL...

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