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Phosphorylation of a Tumor-Derived ASXL2 Epitope Remodels the HLA-Bound Pepti...

Zhang(J),Lv(L),Chen(B),Yi(X) Comput Struct Biotechnol J None

...ASXL2)-derived epitope supported by confident tandem mass spectrometry-based phosphosite localization and detected acros...

Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL-Rela...

Piring(A),Hicks(R),Sloan(J),Ramires-Sanche... Am J Med Genet A 2026-01-00

...ASXL2), or Bainbridge-Ropers syndrome (BRS) (ASXL3). Our findings showed evidence for parental and perceived provider co...

Integrating genomic features for prognosis in Chinese patients with diffuse l...

Han(S),Zhou(L),Zheng(H),Zhao(Y),Cai(Z),He(... Ann Hematol 2026-06-03

...ASXL2 (HR = 2.20; P = 0.048) were significantly associated with poor PFS. A five-gene mutation risk score combined with ...

Neonatal muscle-derived extracellular vesicles containing miR-542-3p rejuvena...

Yuan(F),Chen(Y),Li(W),Zhang(L),Du(R),Xu(S)... Bioact Mater 2026-11-00

...Asxl2-PPARγ, leading to reduced lipid accumulation. At the same time, it suppressed Eef1a1 to activate the AMPK pathway,...

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2-EZH2-Mediated Microtub...

Yin(J),Zhang(M),Liu(W),Shen(W),Li(D),Miao(... Adv Sci (Weinh) 2026-05-00

...ASXL2)-enhancer of zeste homolog 2 (EZH2) axis. Hypoxia downregulates ASXL2 expression, which reduces EZH2 binding to th...

When loss is gain: truncating mutations in additional sex combs (ASXL) gene f...

Nakamura(Y),Nguyen(T),Mor(N),Torio(CJ),Thu... Trends Genet 2026-07-00

...ASXL2, and ASXL3, first described as the additional sex combs (Asx) in Drosophila. The encoded proteins scaffold BAP1-me...

BAP1 dysregulation impairs trophoblast differentiation and contributes to pla...

Doria-Borrell(P),Ferrero-Micó(A),Navarro-S... Cell Death Dis 2026-03-26

...ASXL2 and ASXL3 as upregulated in EO-PE placentas. Enforced BAP1 expression in human trophoblast stem cells reinforced e...

ASXL2 Modulates Chromatin Remodeling to Direct Osteogenesis and Multiple Cell...

Yang(T),Zhou(Y),Han(R),Hu(M),Zeng(B),Shi(H... Int Dent J 2025-10-00

...ASXL2 emerges as a pivotal epigenetic target for craniofacial regeneration. Strategic modulation of ASXL2 activity may o...

Shashi-Pena syndrome with late-onset specific hypogammaglobinaemia and autoim...

Al Ali(A),Saidalani(A),Yeganeh(M),Russell(... BMJ Case Rep 2025-08-04

...ASXL2 gene, presented with a spectrum of manifestations. These encompassed intellectual disability, severe scoliosis, un...

Unconventional structure and function of PHD domains from additional sex comb...

Reddington(CJ),Walsh(AR),Kleffmann(T),Göbl... FEBS J 2025-12-00

...ASXL2 PHD and MBD6 MBD domains, and is required for stable complex formation. Overall, these data suggest an unconventio...

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