Yun(Haiqin),Shi(Ranran),Yang(Qingrui),Zhang(… Sci Rep 2015-09-30

...Rad1 complex plays an important role in DNA damage repair as an up-stream regulator of checkpoint signaling, however lit...

Zhang(Zhenya),Cai(Zeyuan),Li(Kaiming),Fang(Y… Radiat Res 2015-03-11

Rad9, Rad1 and Hus1 are essential genes conserved from yeast to humans. They form a heterotrimer complex (9-1-1 complex)...

Han(Se Hee),Hahm(Soo-Hyun),Tran(An Hue Vy),C… Cell Biosci 2015-08-28

...Rad1 complex. The accumulation of hTopBP1 on chromatin and its subsequent interaction with hRad9 lead to cell cycle arre...

Panigrahi(Sunil K),Hopkins(Kevin M),Lieberma… Nucleic Acids Res 2015-07-31

...RAD1 (9-1-1) complex, it can sense DNA damage and recruit ATR to damage sites. RAD9 binding can enhance activities of me...

Kar(Ananya),Kaur(Manpreet),Ghosh(Tanushree),… Nucleic Acids Res 2015-08-17

...Rad1-Hus1 complex are essential for the alternate mode of ATR activation. In summation, we report that the single-strand...

Lim(Pei Xin),Patel(Darshil R),Poisson(Kelsey… J Biol Chem 2015-09-10

...RAD1 (9-1-1) complex is a heterotrimeric clamp that promotes checkpoint signaling and repair at DNA damage sites. In thi...

Lindsey-Boltz(Laura A),Kemp(Michael G),Capp(… Cell Cycle 2015-09-21

...Rad1, Hus1 interacting nuclear orphan) forms complexes with both the 9-1-1 checkpoint clamp and TopBP1 in human cells ev...

DeStephanis(Darla),McLeod(Melissa),Yan(Shan) Biochem Biophys Res Commun 2015-08-21

...Rad1-Hus1 complex to MMC-induced ICLs on chromatin in the DDR pathway. Notably, domain dissection analysis demonstrates ...

Woodard(Lauren E),De Silva(Ravindra A),Behna… Nucl Med Biol 2015-03-02

...RAD1-24 and [(64)Cu]RAD1-52) was observed in U87-stb-CXCR4 tumors in both PET/CT imaging and biodistribution studies. At...

Ohashi(Eiji),Takeishi(Yukimasa),Ueda(Satoshi… DNA Repair (Amst) 2015-04-21

The checkpoint clamp Rad9-Hus1-Rad1 (9-1-1) interacts with TopBP1 via two casein kinase 2 (CK2)-phosphorylation sites, S...