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Tomas(EJ),Davis(J),Ramos Valdes(Y),Shepher... Cancer Biol Ther 2026-12-31

...BRCA1/2-mutated HGSC, and niraparib is approved for platinum-sensitive recurrent disease. However, research is currently...

Parulekar(M),Kim(YN),Kim(K),Lee(S),No(JH),... Gynecol Oncol 2026-02-00

...BRCA1, BRCA2, PALB2, MLH1, MSH2, MSH6, BRIP1, RAD51C, RAD51D, ATM, and CHEK2) with a variant allele frequency (VAF) of ≥...

Rajaei(A),Mahdavi(P),Chimehrad(R),Zakeri(M... Arch Microbiol 2026-01-12

...BRCA1/2 pathway deficiency) state, which is a homologous recombination DNA repair deficiency, promoting error-prone repa...

Al Assaad(M),Hadi(K),Levine(MF),Guevara(D)... Commun Med (Lond) 2026-01-12

...BRCA1/2 mutations; 24% of HRD cases are BRCA1/2 wild-type. A diverse range of gene alterations involved in HRD are eluci...

Krückel(A),Gocke(J),Hörner(M),Keller(K),Mü... Arch Gynecol Obstet 2026-01-13

...BRCA1/2 variants to include numerous pathogenic variants of other high- and moderate-risk genes. A broad spectrum of gen...

Scheiter(A),Mellin(S),Keil(F),Meier(J),Heu... BMC Med 2026-01-14

...BRCA1/2, including PALB2, ATM, and CHEK2. ADC IHC supported 20 recommendations and two therapy implementations. The inte...

Zhu(X),Jiang(W),Wu(W),Lee(BJ),Menolfi(D),T... Nucleic Acids Res 2026-01-14

...BRCA1-mediated homologous recombination promotes rDNA instability, the non-homologous end joining factor XRCC1, but not ...

Naidoo(M),McNally(O),Scott(CL),Friedlander... JCO Oncol Pract 2026-01-14

...BRCA1/2 testing (HR, 0.66 [95% CI, 0.56 to 0.78], P < .001), and achieving no macroscopic residual disease after primary...

Lim(SYM) Arch Toxicol 2026-04-00

...BRCA1/BARD1 homologs brc-1 and brd-1 repress distinct subsets of cyp-13A genes through H2A ubiquitylation. Collectively,...

Parida(S),Nandi(D),Verma(D),Yi(M),Yende(A)... Cell Commun Signal 2026-01-15

...BRCA1 mutation is observed upon F. nucleatum exposure which is internalized by the cells in a Gal-GalNAc dependent manne...