...BRCA1 /2 should promote an informed decision about genetic testing and anticipation of its outcome, a large number of co...
...BRCA1/2 is beginning to identify other genetic modifiers of BRCA1/2 risk and cancer cluster regions in an attempt to bet...
...BRCA1 activity on the IGF signaling pathway. This study evaluated the effect of BRCA1 on IGF-IR expression.,BRCA1 and IG...
Alternative splicing across exon 11 produces several BRCA1 isoforms. Their proportion varies during the cell cycle, betw...
...BRCA1-positive tumours. Methylation of BRCA1 promoter region was seen in 11/45 cases (24 %). All 11 cases showing BRCA1 ...
...BRCA1/2 mutation carriers are recommended for the removal of ovaries and fimbriae, to reduce the risk of cancer. Treatme...
...BRCA1/2 mutation carriers. Efforts are underway to identify a broader group of patients with genomic susceptibility that...
...BRCA1 overexpression increases ATM transcription and this enhancement is abolished by BRCA1 depletion. Moreover, BRCA1-B...
...BRCA1 mutation were cultured with up to 800 μM RB for one hour or four days, after which their ability to proliferate wa...
...BRCA1, BRCA2, or RAD51 sensitized to ABT-888 (veliparib) alone, FdUrd alone, and FdUrd + ABT-888 (F+A), suggesting that ...
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