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[Perception accuracy of BRCA1/2 mutation predisposition in breast cancer women …

Leblond(Débora),Brédart(Anne),Dolbeault(Sylv… Bull Cancer 2012-08-21

...BRCA1 /2 should promote an informed decision about genetic testing and anticipation of its outcome, a large number of co...

Hereditary gynecologic cancers: risk assessment, counseling, testing and manage…

Ballinger(Lori L) Obstet Gynecol Clin North Am 2012-09-28

...BRCA1/2 is beginning to identify other genetic modifiers of BRCA1/2 risk and cancer cluster regions in an attempt to bet...

BRCA1 is expressed in uterine serous carcinoma (USC) and controls insulin-like …

Amichay(Keren),Kidron(Debora),Attias-Geva(Zo… Int J Gynecol Cancer 2012-10-16

...BRCA1 activity on the IGF signaling pathway. This study evaluated the effect of BRCA1 on IGF-IR expression.,BRCA1 and IG...

Evolutionary constraint helps unmask a splicing regulatory region in BRCA1 exon…

Raponi(Michela),Douglas(Andrew G L),Tammaro(… PLoS One 2012-09-20

Alternative splicing across exon 11 produces several BRCA1 isoforms. Their proportion varies during the cell cycle, betw...

BRCA1-methylated sporadic breast cancers are BRCA-like in showing a basal pheno…

Bal(Amanjit),Verma(Sangeeta),Joshi(Kusum),Si… Virchows Arch 2012-11-06

...BRCA1-positive tumours. Methylation of BRCA1 promoter region was seen in 11/45 cases (24 %). All 11 cases showing BRCA1 ...

[Update on current care guidelines: ovarian cancer].

Leminen(Arto),Auranen(Annika),Bützow(Ralf),H… Duodecim 2012-09-20

...BRCA1/2 mutation carriers are recommended for the removal of ovaries and fimbriae, to reduce the risk of cancer. Treatme...

PARP inhibitors: mechanism of action and their potential role in the prevention…

Basu(Bristi),Sandhu(Shahneen K),de Bono(Joha… Drugs 2012-12-20

...BRCA1/2 mutation carriers. Efforts are underway to identify a broader group of patients with genomic susceptibility that...

Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM trans…

Moiola(Cristian),De Luca(Paola),Cotignola(Ja… Cell Physiol Biochem 2012-12-13

...BRCA1 overexpression increases ATM transcription and this enhancement is abolished by BRCA1 depletion. Moreover, BRCA1-B...

Selective toxicity of rose bengal to ovarian cancer cells in vitro.

Koevary(Steven B) Int J Physiol Pathophysiol Ph… 2012-10-02

...BRCA1 mutation were cultured with up to 800 μM RB for one hour or four days, after which their ability to proliferate wa...

Identification of DNA repair pathways that affect the survival of ovarian cance…

Huehls(Amelia M),Wagner(Jill M),Huntoon(Cath… Mol Pharmacol 2012-12-21

...BRCA1, BRCA2, or RAD51 sensitized to ABT-888 (veliparib) alone, FdUrd alone, and FdUrd + ABT-888 (F+A), suggesting that ...

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